Dyslipidemia – important prognostic unfavorable course risk factor of multifocal atherosclerosis in man after carotid endarterectomy
Abstract
156 man, who were in the surgical department for subsequent reconstructive operation of carotid arteries, were analyzed. Depending on long-term one-year prognosis all patients have been divided into two groups: with unfavorable (93 individuals – 59.6 %) and favorable (63 individuals – 40.4 %) prognosis. It is proved that cardiovascular complications risk such as stroke, transient ischemic attack, myocardial infarction, patients death, and courses deterioration of multifocal atherosclerosis in any arterial region, increase or clinical presentations onset of ischemia in any organ during the first year after surgical procedure increases if there is dyslipidemia in preoperative period, pathologic value of ankle-brachial index (less than 0.9), besides intraoperative characteristic of atherosclerotic plaque (occurrence of intraplaque haemorrhage and extent of atherosclerotic plaque more than 2 cm) in patients. But among this prognostic factors the most important one is the dyslipidemia, herewith statistic regression coefficient of which is 4.64 and Wald index is 43.1. All these data determine maximal prognostic value of dyslipidemia versus other risk factors.
About the Authors
A. V. FrolovRussian Federation
SB RAMS
Federal State Budgetary Institution "Research Institute of Complex Problems of Cardiovascular Diseases"
650002
Pine Boulevard, 6
State Budgetary Educational Institution of Higher Professional Education "Kemerovo State Medical Academy"
650029
st. Voroshilov, 22a
Kemerovo
O. L. Barbarash
Russian Federation
SB RAMS; Russian Ministry of Health
Federal State Budgetary Institution "Research Institute of Complex Problems of Cardiovascular Diseases"
650002
Pine Boulevard, 6
State Budgetary Educational Institution of Higher Professional Education "Kemerovo State Medical Academy"
650029
st. Voroshilov, 22a
Kemerovo
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Review
For citations:
Frolov A.V., Barbarash O.L. Dyslipidemia – important prognostic unfavorable course risk factor of multifocal atherosclerosis in man after carotid endarterectomy. Ateroscleroz. 2013;9(3-4):5-11. (In Russ.)