PATHOPHYSIOLOGICAL AND CLINICAL ASPECTS OF HIGH-DOSE ATORVASTATIN CARDIOPROTECTION IN PATIENTS WITH ACUTE CORONARY SYNDROME
https://doi.org/10.15372/ATER20180312
Abstract
According to modern guidelines, statins are an integral part of treatment of acute coronary heart disease. Cardioprotective effects of atorvastatin in patients with acute coronary syndrome (ACS) are multifaceted and maximally manifested in high doses. The purpose of this review is to analyze international medical literature on the use of high doses of atorvastatin in patients with ACS. The results of the analysis demonstrate significant reduction in post-infarction cardiovascular events, a positive impact on the key pathophysiological processes in ACS.
About the Authors
I. D. Astrakhantseva
District Cardiology Clinic Center of Diagnostics and Cardiovascular Surgery
Russian Federation
Russian Federation
I. A. Urvantseva
District Cardiology Clinic Center of Diagnostics and Cardiovascular Surgery
Russian Federation
Russian Federation
A. S. Vorob’Yev
District Cardiology Clinic Center of Diagnostics and Cardiovascular Surgery
Russian Federation
Russian Federation
K. Yu. Nikolaev
Institute of Internal and Preventive Medicine - Branch of Federal Research Institute of Cytology and Genetics of SB RAS; Surgut State University
Russian Federation
Russian Federation
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Review
For citations:
Astrakhantseva I.D., Urvantseva I.A., Vorob’Yev A.S., Nikolaev K.Yu. PATHOPHYSIOLOGICAL AND CLINICAL ASPECTS OF HIGH-DOSE ATORVASTATIN CARDIOPROTECTION IN PATIENTS WITH ACUTE CORONARY SYNDROME. Ateroscleroz. 2018;14(3):78-83. (In Russ.) https://doi.org/10.15372/ATER20180312
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