Myocardial condition in overweight patients at different stages of rehabilitation after revascularization
https://doi.org/10.52727/2078-256X-2022-18-2-142-147
Abstract
The aim of the study was to study the dynamics of myocardial function indicators in overweight patients at different stages of rehabilitation after coronary revascularization.
Material and methods. This article presents the interim results of prospective study which was conducted at the Tulpar cardiorehabilitation center (Karaganda, Kazakhstan). The study included 135 patients after restoration of blood flow in the coronary arteries (coronary artery bypass grafting, stenting). The average age was 58 ± 6 years. Exclusion criteria: acute myocardial infarction; chronic heart failure, functional class III–IV; acute disorders of cerebral circulation; diabetes mellitus in a state of decompensation; obesity I–III degree. We observed patients in dynamics at three stages of rehabilitation. 41 patients were included in the study at the first stage, 43 – at the second stage and 51 – at the third stage. Patients were included from different stages of rehabilitation. The groups were comparable in terms of the parameters of the structural and functional state of the myocardium, the same age range.
Results. Considering the size of the interventricular septum, the posterior wall of the left ventricle, the relative thickness of the myocardium and the myocardial mass index, it can be noted that statistically significant hypertrophy of the left ventricle was observed in all observation periods (p < 0.05).
Conclusions. In overweight patients who underwent myocardial revascularization surgery, persistent changes in the myocardium remain at the 3rd stage of rehabilitation
About the Authors
A. N. Seitekova
Medical University of Karaganda
Kazakhstan
Kazakhstan
Aizhan N. Seitekova, doctoral student of the 2nd year of study in the specialty «Medicine»
40, Gogol str., Karaganda, 100008
V. B. Molotov-Luchanskiy
Medical University of Karaganda
Kazakhstan
Kazakhstan
Vilen B. Molotov-Luchanskiy, doctor of medical sciences, professor
40, Gogol str., Karaganda, 100008
K. K. Toleubekov
Medical University of Karaganda
Kazakhstan
Kazakhstan
Kuatbek K. Toleubekov, candidate of medical sciences, associate professor, dean of the international medical faculty
40, Gogol str., Karaganda, 100008
B. T. Yekizhanova
Cardiac rehabilitation Center «Tulpar»
Kazakhstan
Kazakhstan
Bayan T. Yekizhanova, director of the cardiac rehabilitation center «Tulpar»
79, Krivoguzov, Karaganda
References
1. WHO information: Cardiovascular diseases. Newsletter No. 317. – January, 2015. http://www.who.int/mediacentre/factsheets/fs317/ru/ (In Russ.)
2. Shpagina O.V., Bondarenko I.Z. The «Obesity Paradox» is another look at the problem of cardiovascular diseases. Literature review. Obesity and Metabolism, 2016; (4): 4–9. (In Russ.)
3. Berdygaliev A.B., Chuenbekova A.B., Kaynarbayeva M.S., Bykybayeva S.A., Sergeantova G.N., Askarov D.M. Studying the prevalence of overweight and obesity among women in Kazakhstan. Bulletin of KazNMU, 2015; (1): 409–413. (In Russ.)
4. Kremlev D.I. The effect of positive fatty degeneration on the development of myocardial infarction. The paradox of obesity. Bulletin of the Russian Military Medical Academy, 2018; (3): 204–211. (In Russ.)
5. Rachel Harrison. «Obesity paradox» not found measuring new cases if cardiovascular disease. Journal LOS ONE, 2017; (12): 14–16.
6. Miklishanskaya S.V., Mazur N.A., Solomasova L.V., Chigineva V.V. «The obesity paradox» and the degree of its proof. Therapeutic Archive, 2020; 92 (4): 84–90. (In Russ.)
7. Komarova I.S., Zhelnov V.V., Andreeva N.V., Dvoretsky L.I. Post-reperfusion syndrome in patients with coronary heart disease after coronary stenting. Clin. Med., 2018; 96 (1): 73–77. (In Russ.)
8. Gramlich Y., Daiber A., Buschmann K., Oelze M., Vahl C.F., Munzel T., Hink U. Oxidative stress in cardiac tissue of patients undergoing coronary artery bypass graft surgery: the effects of overweight and obesity. Oxidative Medicine and Cellular Longevity, 2018; 6598326. doi: 10.1155/2018/6598326
9. Mukherjee D., Ojha C. Оbesity paradox in contemporary cardiology practice. JACC: Cardiovascular Interventions, 2017; 10 (13): 1293–1294. doi: 10.1016/j.jcin.2017.03.048
10. Aronov D., Bubnova M., Iosseliani D., Orekhov A. Clinical efficacy of а medical centre- and home-based cardiac rehabilitation program for patients with coronary heart disease after coronary bypass graft surgery. Arch. Med. Res., 2019; 50 (3): 122–132. doi: 10.1016/j.arcmed.2019.07.007
11. Bilenko M.V. Ischemic and reperfusion injuries of organs. M.: Medicine, 1989. P. 11–34. (In Russ.) Биленко М.В. Ишемические и реперфузионные повреждения органов. М.: Медицина, 1989. С. 11–34.
Review
For citations:
Seitekova A.N., Molotov-Luchanskiy V.B., Toleubekov K.K., Yekizhanova B.T. Myocardial condition in overweight patients at different stages of rehabilitation after revascularization. Ateroscleroz. 2022;18(2):142-147. (In Russ.) https://doi.org/10.52727/2078-256X-2022-18-2-142-147
Views:
256
Email this article 