Novel ultrasonic marker of the thickness of premesenterial fat: the relationship with metabolic indicators and risk factors of cardiovascular diseases

   The aim of present analysis was to investigate the correlations between the ultrasound parameters of subcutaneous and premesenteric fat and cardiovascular risk factors, anthropometric and biochemical parameters and behavioral characteristics in a population sample.

   The object of the study was a random population-based family sample in Octyabrsky district of Novosibirsk (324 men and women aged 18–64 years old). Ultrasound examination of heart, vessels and abdomen was conducted, the thickness of subcutaneous (SF) and premesenteric (PF) fat was measured in every second subject, totally in 163 subjects. In studied population sample of men and women aged 25-64 the value of ultrasonic PF and SF thickness strongly correlated between themselves and were associated with the anthropometric parameters (body mass index, waist-hip ratio, skinfold thickness) measured by standard methods. Ultrasonic indicator of PF thickness positively correlated with the level of blood pressure, proatherogenic lipid parameters (total cholesterol, triglycerides, LDL-choleaterol), blood glucose and plasma insulin levels and was inversely related to the level of HDL- cholesterol. Ultrasonic indicator of SF thickness was similarly correlated with blood pressure and insulin level, but in contrast to the thickness of the PF was not associated with the lipid parameters and blood glucose level.

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