Alzheimer’s disease serum lipids levels in Siberia
Abstract
Background: Previous studies examining the association of serum lipids levels with the risk for development of Alzheimer disease (AD) have been inconclusive.
Objective: To evaluate the serum lipids levels in persons suffering from AD. Methods: 147 patients suffering from AD (according to NINCDS/ADRDA criteria) of both sexes from the Novosibirsk city were examined. Concentration of serum lipids were assessed by enzymatic method. Cognitive functions were determined by Mini-mental State Examination Scale (MMSE).
Results: Patients’ serum lipids levels were corresponded to norms according to European and American Recommendations. Patients’ serum lipids levels were not statistically significant distinguished from those in long-livers from the Novosibirsk city and Yakutia. Statistically significant associations between serum total cholesterol, low-density lipoprotein cholesterol (LDL-CH), high-density lipoprotein cholesterol (HDL-CH) levels and patients’ age, as well as MMSE score were not revealed in correlation analysis.
Conclusion: Serum lipids levels were not associated with risk for development of AD in examined patients’ group.
About the Authors
A. V. Sukhanov
RAMS
Russian Federation
Russian Federation
SB RAMS
Establishment of the Russian Academy of Medical Sciences Research Institute of Therapy
630089
B. Bogatkova str., 175/1
Novosibirsk
M. V. Ivanova
RAMS
Russian Federation
Russian Federation
SB RAMS
Establishment of the Russian Academy of Medical Sciences Research Institute of Therapy
630089
B. Bogatkova str., 175/1
Novosibirsk
Yu. I. Ragino
RAMS
Russian Federation
Russian Federation
SB RAMS
Establishment of the Russian Academy of Medical Sciences Research Institute of Therapy
630089
B. Bogatkova str., 175/1
Novosibirsk
M. I. Voevoda
RAMS
Russian Federation
Russian Federation
SB RAMS
Establishment of the Russian Academy of Medical Sciences Research Institute of Therapy
630089
B. Bogatkova str., 175/1
Novosibirsk
Yu. P. Nikitin
RAMS
Russian Federation
Russian Federation
SB RAMS
Establishment of the Russian Academy of Medical Sciences Research Institute of Therapy
630089
B. Bogatkova str., 175/1
Novosibirsk
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Review
For citations:
Sukhanov A.V., Ivanova M.V., Ragino Yu.I., Voevoda M.I., Nikitin Yu.P. Alzheimer’s disease serum lipids levels in Siberia. Ateroscleroz. 2011;7(2):44-48. (In Russ.)
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