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Атеросклероз

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МОЛЕКУЛЯРНО-ГЕНЕТИЧЕСКИЕ МАРКЕРЫ НАРУШЕНИЙ ЛИПИДНОГО ОБМЕНА И ВНЕЗАПНАЯ СЕРДЕЧНАЯ СМЕРТЬ

Аннотация

Внезапная сердечная смерть продолжает оставаться одной из нерешенных проблем современного здравоохранения. До 50 % летальных исходов вследствие сердечно-сосудистых заболеваний составляет внезапная сердечная смерть, при этом большинство умерших внезапно не имели ранее известного сердечно-сосудистого заболевания. С целью разработки качественной системы диагностики предрасположенности и профилактики развития внезапной сердечной смерти, в первую очередь у лиц без сердечной патологии в анамнезе, исследуются молекулярно-генетические маркеры внезапной сердечной смерти. Одним из факторов риска внезапной сердечной смерти является уровень липидов. В отношении ассоциации с внезапной сердечной смертью изучены однонуклеотидные полиморфизмы генов, ответственных за липидный обмен, таких как CETP, APOE, SREBF2, SCAP, LIPC, USF1, LDLR .

Об авторе

А. А. Иванова
ФГБНУ НИИ терапии и профилактической медицины
Россия


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Рецензия

Для цитирования:


Иванова А.А. МОЛЕКУЛЯРНО-ГЕНЕТИЧЕСКИЕ МАРКЕРЫ НАРУШЕНИЙ ЛИПИДНОГО ОБМЕНА И ВНЕЗАПНАЯ СЕРДЕЧНАЯ СМЕРТЬ. Атеросклероз. 2017;13(2):33-40.

For citation:


Ivanova A.A. MOLECULAR-GENETICAL MARKERS OF LIPID ABNORMALITIES AND SUDDEN CARDIAC DEATH. Ateroscleroz. 2017;13(2):33-40. (In Russ.)

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