Role of endothelial dysfunction in the formation of cognitive impairment
https://doi.org/10.15372/ATER20200104
Abstract
The aim of the study was to examine of endothelial dysfunction markers in patients with dyscirculatory encephalopathy I–II stages.
Material and methods. The study included 30 patients with dyscirculatory encephalopathy I–II stages. All the examinees underwent detection of endothelin-1, desquamated circulating endothelial cells and endothelial NO synthase levels in the blood, reflected endothelial damage. Results of investigation of 21 practically healthy people served as control.
Results. Reliable increasing of endothelial dysfunction markers were detected at initial stage of dyscirculatory encephalopathy, aggravated with the progress of disease.
About the Authors
M. A. Khoreva
Altai State Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
656038, Barnaul, Lenin av., 40
E. N. Vorobyevа
Altai State Medical University of the Ministry of Health of the Russian Federation;
CHUZ «Clinical Hospital “RZD-Medicine” of Barnaul»
Russian Federation
Russian Federation
656038, Barnaul, Lenin av., 40;
656038, Barnaul, Molodezhnaya st., 20
G. I. Shumacher
Altai State Medical University of the Ministry of Health of the Russian Federation;
CHUZ «Clinical Hospital “RZD-Medicine” of Barnaul»
Russian Federation
Russian Federation
656038, Barnaul, Lenin av., 40;
656038, Barnaul, Molodezhnaya st., 20
R. I. Vorobyev
KGBUZ «Regional Clinical Hospital of Emergency Medical Care»
Russian Federation
Russian Federation
656031, Barnaul, Komsomol av., 73
I. A. Batanina
CHUZ «Clinical Hospital “RZD-Medicine” of Barnaul»
Russian Federation
656038, Barnaul, Molodezhnaya st., 20
Russian Federation
656038, Barnaul, Molodezhnaya st., 20
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Review
For citations:
Khoreva M.A., Vorobyevа E.N., Shumacher G.I., Vorobyev R.I., Batanina I.A. Role of endothelial dysfunction in the formation of cognitive impairment. Ateroscleroz. 2020;16(1):22-27. (In Russ.) https://doi.org/10.15372/ATER20200104
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