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The clinical case of cardiac pseudoamyloidosis associated with multiple myeloma

https://doi.org/10.52727/2078-256X-2023-19-2-126-130

Abstract

The clinical case of cardiac pseudoamyloidosis associated with multiple myeloma Cardiac amyloidosis is an infiltrative cardiomyopathy resulting from extracellular deposition of amyloid- a specific protein-polysaccharide complex. This clinical case demonstrates an unverified amyloid-like heart lesion in the presence of unexplained thickening of the wall of an undilated left ventricle and manifestations of restrictive heart failure in a patient with myeloma. The difficulty of establishing an accurate diagnosis lies in the existence of a large number of types of amyloidogenic proteins, the diversity of the clinical picture, the absence of pathognomonic symptoms and of a single non-invasive diagnostic tool for verification.

About the Authors

B. A. Asketova
Research Institutе of Internal and Preventive Medicine – Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences
Russian Federation

Bermet A. Asketova, doctor-resident in the specialty «Cardiology»

175/1, Boris Bogatkov str., Novosibirsk, 630089



N. G. Lozhkina
Federal Research Center for Fundamental and Translational Medicine
Russian Federation

Nataliya G. Lozhkina, doctor of medical sciences, professor, head of clinical and experimental cardiology group, FRC FTM; professor of the immunology, Novosibirsk National Research State University; cardiologist, supervisor of department for treatment of patients with acute coronary syndrome of RCVC № 1 of Municipal Clinical Hospital № 1

2, Timakov str., Novosibirsk, 630117



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Review

For citations:


Asketova B.A., Lozhkina N.G. The clinical case of cardiac pseudoamyloidosis associated with multiple myeloma. Ateroscleroz. 2023;19(2):126-130. (In Russ.) https://doi.org/10.52727/2078-256X-2023-19-2-126-130

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ISSN 2078-256X (Print)
ISSN 2949-3633 (Online)