Apoptosis and apoptotic extracellular vesicular particles in atherogenesis
Abstract
The review summarizes current notions on the role of apoptosis and apoptotic cell-derived extracellular vesicles in atherogenesis. The mechanisms of efferocytosis impairment and its significance in atherosclerotic vulnerable plaque formation are discussed. The data on the pro- and anti-inflammatory effects of apoptotic extracellular vesicular particles are presented.
About the Authors
Yu. Sh. Shwartz
FSBSI «Institute of Internal and Preventive Medicine»
Russian Federation
Russian Federation
630089
Boris Bogatkov str., 175/1
M. I. Chasovskikh
FSBSI «Institute of Internal and Preventive Medicine»
Russian Federation
Russian Federation
630089
Boris Bogatkov str., 175/1
S. V. Cheresiz
FSBSI «Institute of Internal and Preventive Medicine»
Russian Federation
Russian Federation
630089
Boris Bogatkov str., 175/1
M. V. Kruchinina
FSBSI «Institute of Internal and Preventive Medicine»
Russian Federation
Russian Federation
630089
Boris Bogatkov str., 175/1
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For citations:
Shwartz Yu.Sh., Chasovskikh M.I., Cheresiz S.V., Kruchinina M.V. Apoptosis and apoptotic extracellular vesicular particles in atherogenesis. Ateroscleroz. 2015;11(3):79-93. (In Russ.)
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