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Peculiarities of the hospital stage of acute myocardial infarction in patients with varying severity of coronary atherosclerosis on a scale SYNTAX after endovascular treatment

Abstract

   The aim of this study was to investigate characteristics of a hospital phase of acute myocardial infarction in patients with varying degrees of severity of coronary lesions on a scale SYNTAX after endovascular treatment. The severity of coronary lesions on a scale SYNTAX evaluated in 330 consecutive patients (274 men and 56 women), mean age 53.6 ± 8.9 years, with acute myocardial infarction with ST-segment elevation. This patients were divided into three groups: a group with severe coronary disease (SYNTAX ≥ 33), with moderate (SYNTAX from 23 to 32) and low lesion (SYNTAX from 0 to 22). In patients with severe coronary disease had fewer than in patients with low values of the defeat of the Mean Corpuscular Hemoglobin (MCH), Mean Corpuscular Hemoglobin Concentration (MCHC), and total protein, and high density lipoprotein cholesterol. In groups with SYNTAX from 23 to 32 and with SYNTAX ≥ 33 higher blood glucose levels than in the SYNTAX from 0 to 22, and the rate of urea in patients with severe coronary disease exceed the value of this parameter in patients with low and moderate coronary disease. In patients with severe coronary disease are more likely than those with low lesions observed the phenomenon of non-resumption of blood flow after stenting (no-reflow), stent thrombosis, pulmonary edema, acute aneurysm recurrence of heart attack and bleeding. Using binary logistic regression (χ2 model = 25.4, p < 0.001) we revealed that with heavy coronary lesion (SYNTAX ≥ 33) most significantly associated pleural effusion (p < 0.001), the phenomenon of non-renewal blood flow after stenting (no-reflow) (p = 0.004), and acute aneurysm (p = 0.039).

About the Authors

I. A. Urvantseva
Budget Institution of Khmao–Yugra County Cardiology Clinic «Centre for Diagnostics and Cardiovascular Surgery»
Russian Federation

628400

Lenin str., 69/1

Surgut



K. Yu. Nikolaev
Research Institute of Internal and Preventive Medicine
Russian Federation

630089

Boris Bogatkov str., 175/1

Novosibirsk



A. A. Nikolaeva
Research Institute of Internal and Preventive Medicine
Russian Federation

630089

Boris Bogatkov str., 175/1

Novosibirsk



E. V. Milovanova
Budget Institution of Khmao–Yugra County Cardiology Clinic «Centre for Diagnostics and Cardiovascular Surgery»
Russian Federation

628400

Lenin str., 69/1

Surgut



A. A. Seitov
Budget Institution of Khmao–Yugra County Cardiology Clinic «Centre for Diagnostics and Cardiovascular Surgery»
Russian Federation

628400

Lenin str., 69/1

Surgut



G. I. Lifshits
Research Institute of Internal and Preventive Medicine; RAS
Russian Federation

630089

Boris Bogatkov str., 175/1

SB RAS

Institute of Chemical Biology and Fundamental Medicine

630090

Academic Lavrentiev av., 8

Novosibirsk



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Review

For citations:


Urvantseva I.A., Nikolaev K.Yu., Nikolaeva A.A., Milovanova E.V., Seitov A.A., Lifshits G.I. Peculiarities of the hospital stage of acute myocardial infarction in patients with varying severity of coronary atherosclerosis on a scale SYNTAX after endovascular treatment. Ateroscleroz. 2015;11(1):20-26. (In Russ.)

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ISSN 2078-256X (Print)
ISSN 2949-3633 (Online)