Stroke and influence on its development of sleep disorders (epidemiological study based on the who program « MONICA»)

   The purpose of the study. Study of influence of sleep disorders on the risk of stroke for 6 years in men aged 25–64 years.

   Materials and Methods. The WHO Programme «MONICA – psychosocial» in 1994 surveyed men aged 25–64 years, residents of one of the districts of Novosibirsk. A representative sample was formed according to the requirements of the protocol program «MONICA» The study included 657 men (mean age 44,3 ± 0,4). The response was 82.1 %. Socio-demographic and psychosocial indicators were recorded in accordance with the protocol: gender, professional and marital status, education level, and sleep disorders (test «MOPSY»), social support (test Brekman – Sim). Outcomes were considered for the first time encountered cases of fatal and non-fatal stroke in the cohort (47 cases) for 6 years (1994–2000). Statistical analysis was performed using the software package «SPSS-10» Cox proportional regression model was used to estimate the relative risk of stroke.

   Results. Among men arose stroke in 47.1 % of sleep evaluation was «good», 23.5 % – «satisfactory», 29.4 % «bad». The relative risk of stroke in men aged 25–64 for a 6-year period of time was in the 3.9 (p = 0.015) times higher in the evaluation of Sleep «bad» than «good». The relative risk of stroke in the assessment of sleep «bad» was higher in groups: people with incomplete secondary – primary education; hard or moderate physical labor; pensioners; persons evaluating index close contacts and social ties as low.

   Conclusion. The results suggest that sleep disorders contribute significantly to the risk of stroke. Therefore, measures are needed to reduce sleep disorders in the population.

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