Analysis of some biomarkers of dyslipidemia in obstructive sleep apnea and obese patients
Abstract
The aim of this study was to examine the relationship between obstructive sleep apnea (OSA) and the biomarkers of dyslipidemia in obese patients. 66 patients diagnosed with OSA and obesity (Body mass index (BMI) ≥ 30 kg/m2) were enrolled. The study demonstrated higher level of total cholesterol and low-density lipoproteins in patients with severe OSA. There was further significant correlation between elevated levels of triglycerides and low-density lipoproteins and symptoms of hyperactivity of the sympathetic nervous system such as reduced heart rate variability and circadian index according to the daily ECG monitoring.
About the Authors
A. V. Yakovlev
«RR» OJSK; Novosibirsk State Medical University
Russian Federation
Russian Federation
Railway Clinical Hospital on the Station «Novosibirsk-Glavniy»
630003
Vladimirovsky spusk, 2A
630091
Krasny av., 52
Novosibirsk
A. N. Vergazova
«RR» OJSK
Russian Federation
Russian Federation
Railway Clinical Hospital on the Station «Novosibirsk-Glavniy»
630003
Vladimirovsky spusk, 2A
Novosibirsk
N. A. Andryushina
«RR» OJSK
Russian Federation
Russian Federation
Railway Clinical Hospital on the Station «Novosibirsk-Glavniy»
630003
Vladimirovsky spusk, 2A
Novosibirsk
L. P. Plutalova
«RR» OJSK
Russian Federation
Russian Federation
Railway Clinical Hospital on the Station «Novosibirsk-Glavniy»
630003
Vladimirovsky spusk, 2A
Novosibirsk
N. F. Yakovleva
Novosibirsk State Medical University
Russian Federation
Russian Federation
630091
Krasny av., 52
Novosibirsk
O. D. Rymar
RAMS
Russian Federation
Russian Federation
SB RAMS
Research Institute of Internal and Preventive Medicine
630089
Boris Bogatkov str., 175/1
Novosibirsk
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Review
For citations:
Yakovlev A.V., Vergazova A.N., Andryushina N.A., Plutalova L.P., Yakovleva N.F., Rymar O.D. Analysis of some biomarkers of dyslipidemia in obstructive sleep apnea and obese patients. Ateroscleroz. 2014;10(4):32-36. (In Russ.)
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