Factors associated with the presence of high blood pressure in people younger than 45 years old

The aim of the study was to identify factors associated with the presence of high blood pressure (BP) in people under 45 years of age. Material and methods. The study included residents of Novosibirsk 25–44 years old, examined in 2013–2017 in Research Institute of Internal and Preventive Medicine – Branch of the Institute of Cytology and Genetics – 211 persons (46 % men, 54 % women). The examination program included: demographic and social data, survey about smoking and alcohol consumption habits, socioeconomic survey, history of chronic diseases, cardiological survey according to Rose, anthropometry (height, weight, waist circumference, calculation of body mass index, assessment of abdominal obesity), 3 times blood pressure measurement. Blood lipid profile and glucose were measured by enzymatic method using standard Thermo Fisher Scientific reagents on an automatic biochemical analyzer KoneLab 30i (Thermo Fisher Scientific, Finland). Results. According to the results of multivariate logistic regression analysis, the presence of elevated BP in individuals under 45 years of age was associated with glucose levels (odds ratio – OR = 1, 882, 95 % confidence interval – 95 % CI 1.021–3.469, p = 0.043), low-density lipoprotein cholesterol (OR = 1.902, 95 % CI 1.096–3.301, p = 0.022), total cholesterol (OR = 1.919, 95 % CI 1.067–3.452, p = 0.030) and triglycerides (OR = 1.913, 95 % CI 1.010–3.626, p = 0.047) in blood. Conclusions. In young people under 45 years of age, the presence of elevated BP is directly associated with disorders of lipid and carbohydrate metabolism.

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