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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ateroskleroz</journal-id><journal-title-group><journal-title xml:lang="ru">Атеросклероз</journal-title><trans-title-group xml:lang="en"><trans-title>Ateroscleroz</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-256X</issn><issn pub-type="epub">2949-3633</issn><publisher><publisher-name>НИИТПМ-филиал ИЦиГ СО РАН</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52727/2078-256X-2023-19-2-74-83</article-id><article-id custom-type="elpub" pub-id-type="custom">ateroskleroz-901</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Связь потребления пищевых волокон и состояния когнитивной функции в среднем и пожилом возрасте в популяции высокого сердечно-сосудистого риска</article-title><trans-title-group xml:lang="en"><trans-title>The relationship between dietary fiber intake and the state of cognitive function in middle and old age in the population of high cardiovascular risk</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0511-1290</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шишкин</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shishkin</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сергей Владимирович Шишкин, канд. мед. наук, старший научный сотрудник лаборатории клинико-популяционных и профилактических исследований</p><p>630089, г. Новосибирск, ул. Бориса Богаткова, 175/1</p></bio><bio xml:lang="en"><p>Sergey V. Shishkin, candidate of medical sciences, senior research fellow of the laboratory of clinico-populationand preventive studies of therapeutic and endocrine diseases</p><p>175/1, Boris Bogatkov str., Novosibirsk, 630089</p></bio><email xlink:type="simple">shishkin.s34@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2631-8485</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Титаренко</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Titarenko</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анастасия Викторовна Титаренко, канд. мед. наук, научный сотрудник лаборатории этиопатогенеза и клиники внутренних заболеваний</p><p>630089, г. Новосибирск, ул. Бориса Богаткова, 175/1</p></bio><bio xml:lang="en"><p>Anastasiya V. Titarenko, candidate of medical sciences, research fellow of the laboratory of etiopathogenesis and clinic of internal diseases</p><p>175/1, Boris Bogatkov str., Novosibirsk, 630089</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кунцевич</surname><given-names>А. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuntsevich</surname><given-names>A. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Александр Константинович Кунцевич, канд. мед. наук, научный сотрудник лаборатории клинико-популяционных и профилактических исследований терапевтических и эндокринных заболеваний</p><p>630089, г. Новосибирск, ул. Бориса Богаткова, 175/1</p></bio><bio xml:lang="en"><p>Alexander C. Kuntsevich, candidate of medical sciences, Research Fellow of the laboratory of clinico-populationand preventive studies of therapeutic and endocrine diseases</p><p>175/1, Boris Bogatkov str., Novosibirsk, 630089</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2877-1846</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Веревкин</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Verevkin</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Евгений Георгиевич Веревкин, канд. биол. наук, старший научный сотрудник лаборатории этиопатогенеза и клиники внутренних заболеваний</p><p>630089, г. Новосибирск, ул. Бориса Богаткова, 175/1</p></bio><bio xml:lang="en"><p>Evgeny G. Verevkin, candidate of biological sciences, Senior Research Fellow of the laboratory of etiopathogenesis and clinic of internal diseases</p><p>175/1, Boris Bogatkov str., Novosibirsk, 630089</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4716-876X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рымар</surname><given-names>О. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Rymar</surname><given-names>O. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Оксана Дмитриевна Рымар, д-р мед. наук, зав. лабораторией клинико-популяционных и профилактических исследований терапевтических и эндокринных заболеваний</p><p>630089, г. Новосибирск, ул. Бориса Богаткова, 175/1</p></bio><bio xml:lang="en"><p>Oksana D. Rymar, doctor of medical sciences, the head of the laboratory of clinico-population and preventivestudies of therapeutic and endocrine diseases</p><p>175/1, Boris Bogatkov str., Novosibirsk, 630089</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6539-0466</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Малютина</surname><given-names>С. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Malyutina</surname><given-names>S. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Софья Константиновна Малютина, д-р мед. наук, зав. лабораторией этиопатогенеза и клиники внутреннихзаболеваний</p><p>630089, г. Новосибирск, ул. Бориса Богаткова, 175/1</p></bio><bio xml:lang="en"><p>Sofya K. Malyutina, doctor of medical sciences, the head of the laboratory of etiopathogenesis and clinic ofinternal diseases</p><p>175/1, Boris Bogatkov str., Novosibirsk, 630089</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Научно-исследовательский институт терапии и профилактической медицины – филиал Федерального государственного бюджетного научного учреждения «Федеральный исследовательский центр Институт цитологии и генетики Сибирского отделения Российской академии наук»<country>Россия</country></aff><aff xml:lang="en">Research Institutе of Internal and Preventive Medicine – Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>09</day><month>07</month><year>2023</year></pub-date><volume>19</volume><issue>2</issue><fpage>74</fpage><lpage>83</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шишкин С.В., Титаренко А.В., Кунцевич А.К., Веревкин Е.Г., Рымар О.Д., Малютина С.К., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Шишкин С.В., Титаренко А.В., Кунцевич А.К., Веревкин Е.Г., Рымар О.Д., Малютина С.К.</copyright-holder><copyright-holder xml:lang="en">Shishkin S.V., Titarenko A.V., Kuntsevich A.K., Verevkin E.G., Rymar O.D., Malyutina S.K.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ateroskleroz.elpub.ru/jour/article/view/901">https://ateroskleroz.elpub.ru/jour/article/view/901</self-uri><abstract><p>Цель исследования – изучение связи потребления пищевых волокон (ПВ) с состоянием когнитивной функции (КФ) в выборке среднего и пожилого возраста из открытой популяции Новосибирска. Материал и методы. Исследование проведено на случайной выборке из неорганизованной популяции жителей Новосибирска (n = 9360, мужчины и женщины 45–69 лет), обследованной в рамках международного проекта HAPIEE. 4684 человека, составляющие случайную подвыборку из базовой выборки, обследованы в отношении КФ во время 2-го скрининга в 2006–2008 гг. Протокол исследования включал стандартизованное нейропсихологическое тестирование (количественная оценка функции памяти, семантической речевой активности и концентрации внимания) и сбор данных по питанию (потребление ПВ). Отношение шансов оценивали с использованием бинарной логистической регрессии в квартилях потребления продуктов. Результаты. По результатам кросс-секционного анализа в неселективной российской популяционной выборке 45–69 лет выявлена положительная связь показателей КФ с уровнем потребления ПВ, при этом само потребление ПВ в группах мужчин и женщин статистически не различается. Установлены некоторые гендерные особенности, связанные с потреблением ПВ: предположительно, влияние ПВ на семантическую память и речевую активность женщин выражено в большей степени, чем у мужчин. Ранее выявленные данные о том, что образование модифицирует уровень возрастного когнитивного снижения в нашей популяции, справедливы, по-видимому, и в отношении потребления ПВ. Заключение. Потребление ПВ у мужчин и женщин 45–69 лет в популяции высокого сердечно-сосудистого риска позитивно ассоциировано с показателями по всем исследованным доменам КФ. Установленные связи имеют практическое значение для выделения групп риска возрастного когнитивного снижения.</p></abstract><trans-abstract xml:lang="en"><p>Aim of the study was to investigate the relationship between dietary fiber (DF) intake and the state of cognitive function (CF) in a population sample of middle and elderly age in Novosibirsk. Material and methods. The study was conducted on a random population sample from residents of Novosibirsk (n = 9360, men and women 45–69 years old), examined as a part of the international HAPIEE project. A subsample from the baseline population sample (4684 subjects) people who make up a lift from the general baseline population sample were examined for cognitive functions during the 2nd survey in 2006–2008. The examination protocol included standardized neuropsychological testing (quantitative assessment of memory function, semantic and concentration of attention) and collecting the data on nutrition (DF intake). Assessment of odds ratio (OR) was carried out using binary logistics regression by quartiles of nutrients. Results. According to cross-sectional analysis, we revealed a positive association between CF indicators and DF intake in a population sample aged 45–69, while the DF intake in the groups of men and women is not statistically different. Some gender features associated with DF intake have been established: presumably, the influence of DF on semantic memory and speech activity of women is more expressed than in men. Previously identified evidence that education modifies the level of age cognitive decline in our population, apparently, is also relates to DF intake. Conclusions. DF intake in men and women aged 45–69 years in a population of high cardiovascular risk is positively associated with an increase of indicators for all studied CF domains. Established relationships are instrumental in identifying risk groups of age cognitive decline.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>когнитивные функции</kwd><kwd>фактическое питание</kwd><kwd>пищевые волокна</kwd><kwd>популяция</kwd><kwd>старение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cognitive functions</kwd><kwd>actual nutrition</kwd><kwd>dietary fiber</kwd><kwd>population</kwd><kwd>aging</kwd></kwd-group><funding-group xml:lang="ru"><funding-statement>Настоящий анализ поддержан грантом Российского научного фонда (проект № 20-15-00371-П).  Авторы выражают благодарность проекту HAPIEE за доступ к базе данных и сотрудничество. Авторы поддержаны РАН (ГЗ № 122031700094-5).</funding-statement></funding-group><funding-group xml:lang="en"><funding-statement>This analysis was supported by a grant from the Russian Science Foundation (project № 20-15-00371-П).  The authors would like to thank the HAPIEE project for access to the database and collaboration. 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