aterosklerozАтеросклерозAteroscleroz2078-256X2949-3633НИИТПМ-филиал ИЦиГ СО РАН10.52727/2078-256X-2023-19-1-28-34ateroskleroz-887Research ArticleОБЗОРЫ ЛИТЕРАТУРЫLITERATURE REVIEWSВзаимосвязь фибрилляции предсердий с ожирением и хронической сердечной недостаточностьюRelationship of atrial fibrillation with obesity and chronic heart failurehttps://orcid.org/0000-0003-0713-0337ШаронинА. Д.SharoninA. D.

Александр Дмитриевич Шаронин, магистр 2-го года

630090, г. Новосибирск, ул. Пирогова, 1

Alexandr D. Sharonin, master of the 2nd year

1, Pirogov str., Novosibirsk, 630090

https://orcid.org/0000-0002-4832-3197ЛожкинаН. Г.LozhkinaN. G.

Наталья Геннадьевна Ложкина, д-р мед. наук, проф., руководитель группы «Клиническая и экспериментальная кардиология», профессор кафедры иммунологии; кардиолог, куратор отделения для лечения больных с острым коронарным синдромом РСЦ № 1 ГКБ № 1

630117, г. Новосибирск, ул. Тимакова, 2

Nataliya G. Lozhkina, doctor of medical sciences, professor, head of clinical and experimental cardiology group, professor of the immunology; cardiologist, supervisor of department for treatment of patients with acute coronary syndrome of RCVC № 1 of Municipal Clinical Hospital № 1

2, Timakov str., Novosibirsk, 630117

lozhkina.n@mail.ruФедеральное государственное автономное образовательное учреждение высшего образования «Новосибирский национальный исследовательский государственный университет»РоссияNovosibirsk State UniversityRussian FederationФедеральное государственное бюджетное научное учреждение «Федеральный исследовательский центр фундаментальной и трансляционной медицины»РоссияFederal State Budgetary Scientific Institution “Federal Research Center for Fundamental and Translational Medicine”Russian Federation2023040420231912834Copyright © Шаронин А.Д., Ложкина Н.Г., 20232023Шаронин А.Д., Ложкина Н.Г.Sharonin A.D., Lozhkina N.G.This work is licensed under a Creative Commons Attribution 4.0 License.https://ateroskleroz.elpub.ru/jour/article/view/887

В статье представлено современное состояние проблемы фибрилляции предсердий как самого распространенного нарушения сердечного ритма, появление которого значительно ухудшает качество жизни пациентов и уменьшает ее продолжительность. Несомненно, значительное количество больных фибрилляцией предсердий страдают ожирением и сердечной недостаточностью. В обзорной статье рассмотрено понимание фундаментальных патогенетических механизмов фибрилляции предсердий и связанных с ней изменений в клеточной, молекулярной, электрофизиологической и структурной архитектуре предсердий. Использованы сведения по теме из публикаций на основе баз данных PubMed, Google Scholar и eLIBRARY, глубина охвата 5 лет.

The article presents the current state of the problem of atrial fibrillation as the most widespread cardiac rhythm disorder, the occurrence of which significantly worsens the quality of life of patients and reduces their life expectancy. Undoubtedly, a significant number of patients with atrial fibrillation suffer from obesity and heart failure. The review article reviews the understanding of the fundamental pathogenetic mechanisms of atrial fibrillation and the associated changes in the cellular, molecular, electrophysiological, and structural architecture of the atria. Information on the topic from publications based on PubMed, Google Scholar, and eLIBRARY databases was used, with a depth of coverage of 5 years.

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The authors declare that there are no conflicts of interest present.