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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ateroskleroz</journal-id><journal-title-group><journal-title xml:lang="ru">Атеросклероз</journal-title><trans-title-group xml:lang="en"><trans-title>Ateroscleroz</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-256X</issn><issn pub-type="epub">2949-3633</issn><publisher><publisher-name>НИИТПМ-филиал ИЦиГ СО РАН</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52727/2078-256X-2022-18-4-395-404</article-id><article-id custom-type="elpub" pub-id-type="custom">ateroskleroz-867</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LITERATURE REVIEWS</subject></subj-group></article-categories><title-group><article-title>Ассоциации некоторых психосоциальных факторов с сердечно-сосудистыми заболеваниями и приверженностью к медикаментозному лечению у пациентов, перенесших инфаркт миокарда</article-title><trans-title-group xml:lang="en"><trans-title>Associations of psychosocial factors with adherence for medicamental treatment in post-myocardial infarction patients</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Котелкина</surname><given-names>О. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kotelkina</surname><given-names>O. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ольга Сергеевна Котелкина, аспирант кафедры кардиологии</p><p>628412, Ханты-Мансийский автономный округ – Югра, г. Сургут, просп. Ленина, 1</p></bio><bio xml:lang="en"><p>Olga S. Kotelkina, postgraduate student</p><p>1, Lenina ave., Surgut, Khanty-Mansi Autonomous District – Yugra, 628412</p></bio><email xlink:type="simple">kotelkina_os@edu.surgu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Николаев</surname><given-names>К. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikolaev</surname><given-names>K. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Константин Юрьевич Николаев, д-р мед. наук, проф., зав. лабораторией неотложной терапии</p><p>630089, г. Новосибирск, ул. Бориса Богаткова, 175/1</p></bio><bio xml:lang="en"><p>Konstantin Yu. Nikolaev, doctor of medical sciences, professor, head of the laboratory of emergency therapy</p><p>175/1, Boris Bogatkov srt., Novosibirsk, 630089</p></bio><email xlink:type="simple">nikolaevky@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лифшиц</surname><given-names>Г. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Lifshitz</surname><given-names>G. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Галина Израилевна Лифшиц, д-р мед. наук, доцент, зав. лабораторией персонализированной медицины</p><p>630090, г. Новосибирск, просп. Академика Лаврентьева, 8</p></bio><bio xml:lang="en"><p>Galina I. Lifshitz, doctor of medical sciences, associate professor, head of the laboratory of personalized medicine</p><p>8, ave. Academician Lavrentiev, Novosibirsk, 630090</p></bio><email xlink:type="simple">gl62@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Сургутский государственный университет<country>Россия</country></aff><aff xml:lang="en">Surgut State University<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Научно-исследовательский институт терапии и профилактической медицины – филиал Федерального государственного бюджетного научного учреждения «Федеральный исследовательский центр Институт цитологии и генетики Сибирского отделения Российской академии наук»<country>Россия</country></aff><aff xml:lang="en">Research Institute of Internal and Preventive Medicine – Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">Институт химической биологии и фундаментальной медицины Сибирского отделения Российской академии наук<country>Россия</country></aff><aff xml:lang="en">Institute of Chemical Biology and Fundamental Medicine<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>20</day><month>01</month><year>2023</year></pub-date><volume>18</volume><issue>4</issue><fpage>395</fpage><lpage>404</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Котелкина О.С., Николаев К.Ю., Лифшиц Г.И., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Котелкина О.С., Николаев К.Ю., Лифшиц Г.И.</copyright-holder><copyright-holder xml:lang="en">Kotelkina O.S., Nikolaev K.Y., Lifshitz G.I.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ateroskleroz.elpub.ru/jour/article/view/867">https://ateroskleroz.elpub.ru/jour/article/view/867</self-uri><abstract><p>Целью данной статьи является обобщение сведений о связях наиболее значимых психосоциальных факторов с сердечно-сосудистыми заболеваниями и приверженностью к медикаментозному лечению у пациентов, перенесших инфаркт миокарда. В многочисленных исследованиях установлены прямые ассоциации депрессии, личностной тревожности, а также враждебности и невротических расстройств с риском развития инфаркта миокарда и наступлением сердечно-сосудистых событий. Жизненное истощение способствует развитию ишемической болезни сердца и является одним из наиболее важных факторов риска как для мужчин, так и для женщин, а также относительно кратковременным прогностическим маркером возникновения инфаркта миокарда. Определено, что изолированные и одинокие люди подвержены повышенному риску инфаркта миокарда и инсульта, а среди лиц с инфарктом миокарда или инсультом в анамнезе – повышенному риску смерти. Представлены убедительные сведения о том, что узкое социальное окружение и неудовлетворительная социальная поддержка повышают риск развития сердечно-сосудистых заболеваний и ухудшают их прогноз. В ряде исследований установлено, что депрессия и тревожность прямо ассоциированы с низкой приверженностью к медикаментозной терапии у лиц, перенесших инфаркт миокарда. Определено, что социальная поддержка пациентов, перенесших инфаркт миокарда, прямо связана с приверженностью к выполнению рекомендаций по вторичной профилактике и медикаментозному лечению.</p></abstract><trans-abstract xml:lang="en"><p>The aim of this article is to summarize information about the relationship of the most significant psychosocial factors with cardiovascular disease and adherence to medicamental treatment in patients with myocardial infarction. Numerous studies have established direct associations of depression, personal anxiety, as well as hostility and neurotic disorders with the risk of developing myocardial infarction and the onset of cardiovascular events. Exhaustion contributes to the development of coronary heart disease and is one of the most important risk factors for both men and women, as well as a relatively short-term prognostic marker for the occurrence of myocardial infarction. It has been determined that isolated and lonely people are at increased risk of myocardial infarction and stroke, and among those with a history of myocardial infarction or stroke, an increased risk of death. There is convincing evidence that a narrow social environment and poor social support increase the risk of developing cardiovascular diseases and worsen their prognosis. A number of studies have found that depression and anxiety are directly associated with low adherence to drug treatment in patients who have had myocardial infarction. It has been determined that social support for patients who have had myocardial infarction is directly related to adherence to the implementation of recommendations for secondary prevention and drug treatment.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>инфаркт миокарда</kwd><kwd>сердечно-сосудистые заболевания</kwd><kwd>психосоциальные факторы</kwd><kwd>приверженность к медикаментозной терапии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>myocardial infarction</kwd><kwd>cardiovascular diseases</kwd><kwd>psychosocial factors</kwd><kwd>adherence to drug treatment</kwd></kwd-group><funding-group xml:lang="ru"><funding-statement>Исследование выполнено в рамках ПНИ НИИ терапии и профилактической медицины – филиала Института цитологии и генетики СО РАН «Совершенствование методов реабилитации больных в позднем периоде инфаркта миокарда в Сибири», № FWNR2022-0028.</funding-statement></funding-group><funding-group xml:lang="en"><funding-statement>The study was carried out within the framework of applied scientific research in Research Institute of Internal and Preventive Medicine – Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences “Improvement of methods for the rehabilitation of patients in the late period of myocardial infarction in Siberia”, N FWNR-2022-0028.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Manfrini O., Cenko E., Bugiardini R. 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