aterosklerozАтеросклерозAteroscleroz2078-256X2949-3633НИИТПМ-филиал ИЦиГ СО РАН10.52727/2078-256X-2022-18-4-388-394ateroskleroz-865Research ArticleОБЗОРЫ ЛИТЕРАТУРЫLITERATURE REVIEWSРоль адипокинов в формировании кардиометаболических нарушений у человекаThe role of adipokines in the development of cardiometabolic disorders in humanshttps://orcid.org/0000-0002-1645-5523АлфёроваВ. И.AlferovaV. I.

Влада Игоревна Алфёрова, аспирант

eLibrary SPIN: 1129-0599

630089, г. Новосибирск, ул. Бориса Богаткова, 175/1

Vlada I. Alferova, MD, postgraduate student

eLibrary SPIN: 1129-0599

 

lady.alfyorova2009@yandex.ruhttps://orcid.org/0000-0003-4716-876XМустафинаС. В.MustafinaS. V.

Светлана Владимировна Мустафина, д-р мед. нау

eLibrary SPIN: 8395-1395

630089, г. Новосибирск, ул. Бориса Богаткова, 175/1

Svetlana V. Mustafina, doctor of medical sciences

eLibrary SPIN: 8395-1395

svetlana3548@gmail.comНаучно-исследовательский институт терапии и профилактической медицины – филиал Федерального государственного бюджетного научного учреждения «Федеральный исследовательский центр Институт цитологии и генетики Сибирского отделения Российской академии наук»РоссияResearch Institutе of Internal and Preventive Medicine, Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of SciencesRussian Federation202219012023184388394Copyright © Алфёрова В.И., Мустафина С.В., 20232023Алфёрова В.И., Мустафина С.В.Alferova V.I., Mustafina S.V.This work is licensed under a Creative Commons Attribution 4.0 License.https://ateroskleroz.elpub.ru/jour/article/view/865

В обзоре представлены результаты исследований возможных механизмов, посредством которых реализуется влияние адипокинов на сердечно-сосудистую систему. Проанализированы такие адипокины и цитокины, как адипонектин, лептин, резистин, адипсин, интерлейкин-6, фактор некроза опухоли α. Приводятся данные о патогенетических и клинических особенностях выработки данных биологически активных веществ и их влияния на метаболизм. Проанализированы тематические источники из баз данных PubMed, РИНЦ.

The review presents the results of studies of possible mechanisms through which the effect of adipokines on the cardiovascular system is realized. Such adipokines and cytokines as adiponectin, leptin, resistin, adipsin, interleukin 6, tumor necrosis factor α are analyzed. Data are given on the pathogenetic and clinical features of the production of these biologically active substances and their effect on metabolism. Thematic sources from PubMed and RSCI databases are analyzed.

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The authors declare that there are no conflicts of interest present.