aterosklerozАтеросклерозAteroscleroz2078-256X2949-3633НИИТПМ-филиал ИЦиГ СО РАН10.15372/ATER20180309ateroskleroz-83Research ArticleОБЗОРЫREVIEWSПРОТЕОМНЫЕ ИССЛЕДОВАНИЯ ПРИ АТЕРОСКЛЕРОЗЕPROTEOMIC STUDIES IN ATHEROSCLEROSISРагиноЮ. И.RaginoYu. I.ragino@mail.ruСтахнёваЕ. М.StakhnevaE. M.stahneva@yandex.ruНИИТПМ - филиал ИЦиГ СО РАНInstitute of Internal and Preventive Medicine - Branch of Federal Research Institute of Cytology and genetics of SB RAS2018270920191435663Copyright © Рагино Ю.И., Стахнёва Е.М., 20192019Рагино Ю.И., Стахнёва Е.М.Ragino Y.I., Stakhneva E.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://ateroskleroz.elpub.ru/jour/article/view/83

Обзор посвящен анализу литературных данных, связанных с ролью протеомных исследований при изучении атеросклеротических сердечно-сосудистых заболеваний. Приводятся результаты исследований по поиску новых протеомных потенциальных биомаркеров коронарного атеросклероза, ишемической болезни сердца, острого коронарного синдрома, инфаркта миокарда, атеросклероза сонных артерий, а также протеомных маркеров нестабильной атеросклеротической бляшки. Обсуждается, что протеомный анализ является перспективной развивающейся областью исследований.

The review is devoted to the analysis of literature data related to the role of proteomic technologies in the study of atherosclerotic cardiovascular diseases. The results of research on the search for new proteomic potential biomarkers of coronary atherosclerosis, coronaryc heart disease, acute coronary syndrome, myocardial infarction, carotid atherosclerosis, and proteomic markers of unstable atherosclerotic plaque are presented. It is discussed that proteomic analysis is a promising developing field of research.

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The authors declare that there are no conflicts of interest present.