<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ateroskleroz</journal-id><journal-title-group><journal-title xml:lang="ru">Атеросклероз</journal-title><trans-title-group xml:lang="en"><trans-title>Ateroscleroz</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-256X</issn><issn pub-type="epub">2949-3633</issn><publisher><publisher-name>НИИТПМ-филиал ИЦиГ СО РАН</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ateroskleroz-753</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Взаимосвязь сердечно-сосудистых заболеваний и метаболического синдрома</article-title><trans-title-group xml:lang="en"><trans-title>The relationship of cardiovascular disease and metabolic syndrome</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Воробьева</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Vorobyova</surname><given-names>E. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Елена Николаевна Воробьева, д-р мед. наук, проф.</p><p>ГБОУ ВП «Алтайский государственный медицинский университет»</p><p>кафедра биохимии и клинической лабораторной диагностики</p><p>656049</p><p>просп. Ленина, 40</p><p>Барнаул</p></bio><bio xml:lang="en"><p>656049</p><p>Lenin av., 40</p><p>Barnaul</p></bio><email xlink:type="simple">elenavorobyova@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фомичева</surname><given-names>М. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Fomicheva</surname><given-names>M. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мария Леонидовна Фомичева, канд. мед. наук, зав. лабораторией</p><p>лаборатория профилактической медицины</p><p>630089</p><p>ул. Бориса Богаткова, 175/1</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>630089</p><p>Boris Bogatkov str., 175/1</p><p>Novosibirsk</p></bio><email xlink:type="simple">elenavorobyova@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Воробьев</surname><given-names>Р. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Vorobyov</surname><given-names>R. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Роман Иосифович Воробьев, канд. мед. наук, врач-кардиолог</p><p>кардиоинфарктное отделение</p><p>отделение интенсивной терапии</p><p>656049</p><p>Песчаная, 89-270</p><p>Барнаул</p><p> </p></bio><bio xml:lang="en"><p>656049</p><p>Peschanaya str., 89–270</p><p>Barnaul</p></bio><email xlink:type="simple">elenavorobyova@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шарлаева</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sharlaeva</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Елена Анатольевна Шарлаева, канд. биол. наук, доцент</p><p>кафедра экологии, биохимии и биотехнологии</p><p>656049</p><p>просп. Ленина, 61</p><p>Барнаул</p></bio><bio xml:lang="en"><p>656049</p><p>Lenin av., 61</p><p>Barnaul</p></bio><email xlink:type="simple">sharlaeva1@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соколова</surname><given-names>Г. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Sokolova</surname><given-names>G. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Галина Геннадьевна Соколова, д-р биол. наук, проф., зав. кафедрой</p><p>кафедра экологии, биохимии и биотехнологии</p><p>656049</p><p>просп. Ленина, 61</p><p>Барнаул</p></bio><bio xml:lang="en"><p>656049</p><p>Lenin av., 61</p><p>Barnaul</p></bio><email xlink:type="simple">dean@bio.asu.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рудакова</surname><given-names>Д. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Rudakova</surname><given-names>D. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Диана Михайловна Рудакова, зам. главного врача</p><p>656024</p><p>ул. Ляпидевского, 1</p><p>Барнаул</p></bio><bio xml:lang="en"><p>656024</p><p>Lyapidevskiy str., 1</p><p>Barnaul</p></bio><email xlink:type="simple">elenavorobyova@yandex.ru</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ефремушкина</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Efremushkina</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анна Александровна Ефремушкина,  д-р мед. наук, проф.</p><p>ГБОУ ВП «Алтайский государственный медицинский университет»</p><p>кафедра госпитальной терапии</p><p>656049</p><p>просп. Ленина, 40</p><p>Барнаул</p></bio><bio xml:lang="en"><p>656049</p><p>Lenin av., 40</p><p>Barnaul</p></bio><email xlink:type="simple">elenavorobyova@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Казызаева</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kazyzaeva</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анна Сергеевна Казызаева, канд. биол. наук, начальник управления</p><p>ГБОУ ВП «Алтайский государственный медицинский университет»</p><p>научное управление</p><p>656049</p><p>просп. Ленина, 40</p><p>Барнаул</p></bio><bio xml:lang="en"><p>656049</p><p>Lenin av., 40</p><p>Barnaul</p></bio><email xlink:type="simple">kazyzaeva@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Минздрав России<country>Россия</country></aff><aff xml:lang="en">Altai State Medical University<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">ФГБНУ «НИИ терапии и профилактической медицины»<country>Россия</country></aff><aff xml:lang="en">Institute of Internal and Preventive Medicine<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">КГБУЗ «Городская больница № 1»<country>Россия</country></aff><aff xml:lang="en">Sity Hospital № 1<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru">ФГБОУ ВПО «Алтайский государственный университет»<country>Россия</country></aff><aff xml:lang="en">Altai State University<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru">КБУЗ «Краевая клиническая больница»<country>Россия</country></aff><aff xml:lang="en">Regional Clinical Hospital<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>17</day><month>04</month><year>2022</year></pub-date><volume>11</volume><issue>2</issue><fpage>50</fpage><lpage>57</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Воробьева Е.Н., Фомичева М.Л., Воробьев Р.И., Шарлаева Е.А., Соколова Г.Г., Рудакова Д.М., Ефремушкина А.А., Казызаева А.С., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Воробьева Е.Н., Фомичева М.Л., Воробьев Р.И., Шарлаева Е.А., Соколова Г.Г., Рудакова Д.М., Ефремушкина А.А., Казызаева А.С.</copyright-holder><copyright-holder xml:lang="en">Vorobyova E.N., Fomicheva M.L., Vorobyov R.I., Sharlaeva E.A., Sokolova G.G., Rudakova D.M., Efremushkina A.A., Kazyzaeva A.S.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ateroskleroz.elpub.ru/jour/article/view/753">https://ateroskleroz.elpub.ru/jour/article/view/753</self-uri><abstract><p>   Сердечно-сосудистые заболевания (ССЗ) являются основной причиной смертности и инвалидизации населения. Фактором риска сердечно-сосудистых осложнений, а также сахарного диабета 2 типа (СД) и ожирения является инсулинорезистентность – основа метаболического синдрома (МС). Рассматривается взаимосвязь ССЗ и МС, обсуждаются лабораторные маркеры и антропометрические параметры, которые могут выступать значимыми индикаторами предрасположенности к метаболическим изменениям, ассоциированным с риском ССЗ.</p></abstract><trans-abstract xml:lang="en"><p>   Cardiovascular diseases are the leading cause of death and disability in the population. A risk factor for cardiovascular disease, as well as type 2 diabetes, obesity is insulin resistance – the basis of the metabolic syndrome. The article discusses the relationship of cardiovascular disease and metabolic syndrome, also laboratory markers and anthropometric parameters, which can be important indicators of predisposition to metabolic changes associated with the cardiovascular disease risk.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сердечно-сосудистые заболевания</kwd><kwd>атеросклероз</kwd><kwd>инсулинорезистентность</kwd><kwd>метаболический синдром</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cardiovascular diseases</kwd><kwd>atherosclerosis</kwd><kwd>insulin resistance</kwd><kwd>metabolic syndrome</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Кухарчук В. В. Дислипидемии и сердечно-сосудистые заболевания / В. В. Кухарчук // Consilium Medicum. – 2009. – Т. 11, № 5. – С. 61–64.</mixed-citation><mixed-citation xml:lang="en">Кухарчук В. В. Дислипидемии и сердечно-сосудистые заболевания / В. В. Кухарчук // Consilium Medicum. – 2009. – Т. 11, № 5. – С. 61–64.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Dias R. G., Negrгo C. E., Krieger M. H. Nitric oxide and the cardiovascular system: cell activation, vascular reactivity and genetic variant // Arq. Bras. Cardiol. 2011. Vol. 96, N 1. P. 68–75.</mixed-citation><mixed-citation xml:lang="en">Dias R. G., Negrгo C. E., Krieger M. H. Nitric oxide and the cardiovascular system: cell activation, vascular reactivity and genetic variant // Arq. Bras. Cardiol. 2011. Vol. 96, N 1. P. 68–75.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Ribeiro F., Alves A. J., Teixeira M. et al. Endothelial function and atherosclerosis: circulatory markers with clinical usefulness // Rev. Port. Cardiol. 2009. Vol. 28, N 10. P. 1121–1151.</mixed-citation><mixed-citation xml:lang="en">Ribeiro F., Alves A. J., Teixeira M. et al. Endothelial function and atherosclerosis: circulatory markers with clinical usefulness // Rev. Port. Cardiol. 2009. Vol. 28, N 10. P. 1121–1151.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Teerlink J. R. Endothelins: Pathophysiology and treatment implications in chronic heart failure // Curr. Heart Failure Reports. 2005. Vol. 2. P. 191–197.</mixed-citation><mixed-citation xml:lang="en">Teerlink J. R. Endothelins: Pathophysiology and treatment implications in chronic heart failure // Curr. Heart Failure Reports. 2005. Vol. 2. P. 191–197.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Schiffrin E. L., Touyz R. M. Vascular biology of endothelin // J. Cardiovasc. Pharmacol. 1998. Vol. 32 (Suppl 3). P. S2–S13.</mixed-citation><mixed-citation xml:lang="en">Schiffrin E. L., Touyz R. M. Vascular biology of endothelin // J. Cardiovasc. Pharmacol. 1998. Vol. 32 (Suppl 3). P. S2–S13.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Henry P., Thomas A. F., Benetos et al. Impaired fasting glucose, blood pressure and cardiovascular disease mortality // Hypertension. 2002. Vol. 40. P. 458–463.</mixed-citation><mixed-citation xml:lang="en">Henry P., Thomas A. F., Benetos et al. Impaired fasting glucose, blood pressure and cardiovascular disease mortality // Hypertension. 2002. Vol. 40. P. 458–463.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Boucher J., Masri B., Daviaud D. et al. Apelin, a newly identified adipokine up-regulated by insulin and obesity // Endocrinology. 2005. N 146. P. 1764–1771.</mixed-citation><mixed-citation xml:lang="en">Boucher J., Masri B., Daviaud D. et al. Apelin, a newly identified adipokine up-regulated by insulin and obesity // Endocrinology. 2005. N 146. P. 1764–1771.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Brownlee M. Biochemistry and molecular cell biology of diabetic complications // Nature. 2001. N 414. P. 813–820.</mixed-citation><mixed-citation xml:lang="en">Brownlee M. Biochemistry and molecular cell biology of diabetic complications // Nature. 2001. N 414. P. 813–820.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Fornoni A., Raij L. Metabolic syndrome and endothelial dysfunction // Curr. Hypertens. Rep. 2005. Vol. 7. P. 88–95.</mixed-citation><mixed-citation xml:lang="en">Fornoni A., Raij L. Metabolic syndrome and endothelial dysfunction // Curr. Hypertens. Rep. 2005. Vol. 7. P. 88–95.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Scherrer U., Sartori C. Defective nitric oxide synthesis: a link between metabolic insulin resistance, sympathetic overactivity and cardiovascular morbidity // Eur. J. Endocrinol. 2000. Vol. 142. P. 315–323.</mixed-citation><mixed-citation xml:lang="en">Scherrer U., Sartori C. Defective nitric oxide synthesis: a link between metabolic insulin resistance, sympathetic overactivity and cardiovascular morbidity // Eur. J. Endocrinol. 2000. Vol. 142. P. 315–323.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Ferrannini E. Insulin and Blood Pressure: Connected on a Circumference? // Hypertension. 2005. Vol. 45. Р. 347–348.</mixed-citation><mixed-citation xml:lang="en">Ferrannini E. Insulin and Blood Pressure: Connected on a Circumference? // Hypertension. 2005. Vol. 45. Р. 347–348.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Cohen A. W., Combs T. P., Scherer P. E., Lisanti M. P. Role of caveolin and caveolae in insulin signaling and diabetes // Am. J. Physiol. Endocrinol. Metab. 2003. N 285. P. 1151–1160.</mixed-citation><mixed-citation xml:lang="en">Cohen A. W., Combs T. P., Scherer P. E., Lisanti M. P. Role of caveolin and caveolae in insulin signaling and diabetes // Am. J. Physiol. Endocrinol. Metab. 2003. N 285. P. 1151–1160.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Razani B., Woodman S. E., Lisanti M. P. Caveolae: From Cell Biology to Animal Physiology // Pharmacol. Rev. 2002. Vol. 54. P. 431–467.</mixed-citation><mixed-citation xml:lang="en">Razani B., Woodman S. E., Lisanti M. P. Caveolae: From Cell Biology to Animal Physiology // Pharmacol. Rev. 2002. Vol. 54. P. 431–467.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Behrendt D., Ganz P. Endothelial function: from vascular biology to clinical applications // Am. J. Cardiol. 2002. N 90. P. 40–48.</mixed-citation><mixed-citation xml:lang="en">Behrendt D., Ganz P. Endothelial function: from vascular biology to clinical applications // Am. J. Cardiol. 2002. N 90. P. 40–48.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Hansson G. K. Inflammation, atherosclerosis, and coronary artery disease // N. Engl. J. Med. 2005. Vol. 352. P. 1685–1695.</mixed-citation><mixed-citation xml:lang="en">Hansson G. K. Inflammation, atherosclerosis, and coronary artery disease // N. Engl. J. Med. 2005. Vol. 352. P. 1685–1695.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Libby P., Ridker P. M. Inflammation and atherosclerosis: role of C-Reactive protein in risk assessment // Am. J. Med. 2004. Vol. 116. P. 9–16.</mixed-citation><mixed-citation xml:lang="en">Libby P., Ridker P. M. Inflammation and atherosclerosis: role of C-Reactive protein in risk assessment // Am. J. Med. 2004. Vol. 116. P. 9–16.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Oliveira G. H. Novel serologic markers of cardiovascular risk // Curr. Atheroscler. Rep. 2005. Vol. 7. P. 148–154.</mixed-citation><mixed-citation xml:lang="en">Oliveira G. H. Novel serologic markers of cardiovascular risk // Curr. Atheroscler. Rep. 2005. Vol. 7. P. 148–154.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Bhakdi S., Torzewski M., Klouche M., Hemmes M. Complement and atherogenesis. Binding of CRP to degraded, nonoxidized LDL enhances complement activation // Arterioscler. Thromb. Vasc. Biol. 1999. N 19. P. 2348–2354.</mixed-citation><mixed-citation xml:lang="en">Bhakdi S., Torzewski M., Klouche M., Hemmes M. Complement and atherogenesis. Binding of CRP to degraded, nonoxidized LDL enhances complement activation // Arterioscler. Thromb. Vasc. Biol. 1999. N 19. P. 2348–2354.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Verma S. C-reactive protein upregulates the nuclear factor-κB signal transduction pathway in saphenous vein endothelial cells: implications for atherosclerosis and restenosis // J. Thorac. Cardiovasc. Surg. 2003. Vol. 126. P. 1886–1891.</mixed-citation><mixed-citation xml:lang="en">Verma S. C-reactive protein upregulates the nuclear factor-κB signal transduction pathway in saphenous vein endothelial cells: implications for atherosclerosis and restenosis // J. Thorac. Cardiovasc. Surg. 2003. Vol. 126. P. 1886–1891.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Zee R. Y., Ridker P. M. Polymorphism in the human C-reactive protein (CRP) gene, plasma concentrations of CRP, and the risk of future arterial thrombosis // Atherosclerosis. 2002. Vol. 162. P. 217–219.</mixed-citation><mixed-citation xml:lang="en">Zee R. Y., Ridker P. M. Polymorphism in the human C-reactive protein (CRP) gene, plasma concentrations of CRP, and the risk of future arterial thrombosis // Atherosclerosis. 2002. Vol. 162. P. 217–219.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Williams T. N., Zhang C. X., Game B. A. et al. C-Reactive Protein Stimulates MMP-1 Expression in U937 Histiocytes Through FcγRII and Extracellular Signal-Regulated Kinase Pathway. An Implication of CRP Involvement in Plaque Destabilization // Arterioscler. Thromb. Vasc. Biol. 2004. Vol. 24. P. 61–66.</mixed-citation><mixed-citation xml:lang="en">Williams T. N., Zhang C. X., Game B. A. et al. C-Reactive Protein Stimulates MMP-1 Expression in U937 Histiocytes Through FcγRII and Extracellular Signal-Regulated Kinase Pathway. An Implication of CRP Involvement in Plaque Destabilization // Arterioscler. Thromb. Vasc. Biol. 2004. Vol. 24. P. 61–66.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Koschinsky M. L. Lipoprotein(a) and atherosclerosis: New perspectives on the mechanism of action of an enigmatic lipoprotein // Curr. Atheroscler. Rep. 2005. Vol. 7. P. 389–395.</mixed-citation><mixed-citation xml:lang="en">Koschinsky M. L. Lipoprotein(a) and atherosclerosis: New perspectives on the mechanism of action of an enigmatic lipoprotein // Curr. Atheroscler. Rep. 2005. Vol. 7. P. 389–395.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Lee D. K., Cheng R., Nguyen T., Fan T. et al. Characterization of apelin, the ligand for the APJ receptor // Neurochem. 2000. Vol. 74. P. 34–41.</mixed-citation><mixed-citation xml:lang="en">Lee D. K., Cheng R., Nguyen T., Fan T. et al. Characterization of apelin, the ligand for the APJ receptor // Neurochem. 2000. Vol. 74. P. 34–41.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Folino A., Montarolo P. G., Samaja M., Rastaldo R. Effects of apelin on the cardiovascular system // Heart Fail Rev. 2015. Feb 5. [Epub ahead of print].</mixed-citation><mixed-citation xml:lang="en">Folino A., Montarolo P. G., Samaja M., Rastaldo R. Effects of apelin on the cardiovascular system // Heart Fail Rev. 2015. Feb 5. [Epub ahead of print].</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Kleinz M. J., Davenport A. P. Immunocytochemical localization of the endogenous vasoactive peptide apelin to human vascular and endocardial endothelial cells // Regul. Pept. 2004. Vol. 118. P. 25–119.</mixed-citation><mixed-citation xml:lang="en">Kleinz M. J., Davenport A. P. Immunocytochemical localization of the endogenous vasoactive peptide apelin to human vascular and endocardial endothelial cells // Regul. Pept. 2004. Vol. 118. P. 25–119.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Falcгo-Pires I., Leite-Moreira A. F. Apelin: a novel neurohumoral modulator of the cardiovascular system. Pathophysiologic importance and potential use as a therapeutic target // Rev. Port. Cardiol. 2005. Oct. 24 (10). P. 1263–1276.</mixed-citation><mixed-citation xml:lang="en">Falcгo-Pires I., Leite-Moreira A. F. Apelin: a novel neurohumoral modulator of the cardiovascular system. Pathophysiologic importance and potential use as a therapeutic target // Rev. Port. Cardiol. 2005. Oct. 24 (10). P. 1263–1276.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Farkasfalvi K., Stagg M. A., Coppen S. R. et al. Direct effects of apelin on cardiomyocyte contractility and electrophysiology // Biochem. Biophys. Res. Commun. 2007. N 357 (4). P. 889–895.</mixed-citation><mixed-citation xml:lang="en">Farkasfalvi K., Stagg M. A., Coppen S. R. et al. Direct effects of apelin on cardiomyocyte contractility and electrophysiology // Biochem. Biophys. Res. Commun. 2007. N 357 (4). P. 889–895.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Tatemoto K., Takayama K., Zou M. X. et al. The novel peptide apelin lowres blood pressure via a nitric oxide-dependent mechanism // Regul. Pept. 2001. N 99 (2-3). P. 87–92.</mixed-citation><mixed-citation xml:lang="en">Tatemoto K., Takayama K., Zou M. X. et al. The novel peptide apelin lowres blood pressure via a nitric oxide-dependent mechanism // Regul. Pept. 2001. N 99 (2-3). P. 87–92.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Lee D. K., Saldivia V. R., Nguyen T., Cheng R. et аl. Modification of the terminal residue of apelin-13 antagonizes its hypotensive action // Endocrinology. 2005. N 146 (1). P. 231–236.</mixed-citation><mixed-citation xml:lang="en">Lee D. K., Saldivia V. R., Nguyen T., Cheng R. et аl. Modification of the terminal residue of apelin-13 antagonizes its hypotensive action // Endocrinology. 2005. N 146 (1). P. 231–236.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Chandrasekaran B., Dar O., McDonagh T. The role of apelin in cardiovascular function and heart failure // Eur. J. Heart Fail. 2008. N 10. P. 725–732.</mixed-citation><mixed-citation xml:lang="en">Chandrasekaran B., Dar O., McDonagh T. The role of apelin in cardiovascular function and heart failure // Eur. J. Heart Fail. 2008. N 10. P. 725–732.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Chong K. S., Gardner R. S., Morton J. J. et al. Plasma concentrations of the novel peptide apelin are decreased in patients with chronic heart failure // Eur. J. Heart Fail. 2006. N 8 (4). P. 355–360.</mixed-citation><mixed-citation xml:lang="en">Chong K. S., Gardner R. S., Morton J. J. et al. Plasma concentrations of the novel peptide apelin are decreased in patients with chronic heart failure // Eur. J. Heart Fail. 2006. N 8 (4). P. 355–360.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Glassford A. J., Yue P., Sheikh A. Y. et al. HIF-1 regulates hypoxia- and insulin-induced expression of apelin in adipocytes // Am. J. Physiol. Endocrinol. Metab. 2007. N 293 (6). Р. 1590–1596.</mixed-citation><mixed-citation xml:lang="en">Glassford A. J., Yue P., Sheikh A. Y. et al. HIF-1 regulates hypoxia- and insulin-induced expression of apelin in adipocytes // Am. J. Physiol. Endocrinol. Metab. 2007. N 293 (6). Р. 1590–1596.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Boucher J. А., Masri B., Le Daviaud D. еt al. Newly Identified Adipokine Up-Regulated by Insulin and Obesity // Apelin. Endocrinol. 2005. N 146 (4). Р. 1764–1771.</mixed-citation><mixed-citation xml:lang="en">Boucher J. А., Masri B., Le Daviaud D. еt al. Newly Identified Adipokine Up-Regulated by Insulin and Obesity // Apelin. Endocrinol. 2005. N 146 (4). Р. 1764–1771.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Soriguer F., Garrido-Sanchez L., Garcia-Serrano S. еt al. Apelin levels are increased in morbidly obese subjects with type 2 diabetes mellitus // Obesity Surgery. 2009. Vol. 19. P. 1574–1580.</mixed-citation><mixed-citation xml:lang="en">Soriguer F., Garrido-Sanchez L., Garcia-Serrano S. еt al. Apelin levels are increased in morbidly obese subjects with type 2 diabetes mellitus // Obesity Surgery. 2009. Vol. 19. P. 1574–1580.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Higuchi K., Masaki М., Gotoh K. et al. Apelin, an APJ receptor ligand, regulates body adiposity and favors the messenger ribonucleic acid expression of uncoupling proteins in mice // Endocrinology. 2007. Vol. 148. P. 2690–2697.</mixed-citation><mixed-citation xml:lang="en">Higuchi K., Masaki М., Gotoh K. et al. Apelin, an APJ receptor ligand, regulates body adiposity and favors the messenger ribonucleic acid expression of uncoupling proteins in mice // Endocrinology. 2007. Vol. 148. P. 2690–2697.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Despres J.-P. Abdominal obesity as an important component of insulin resistance syndrome // Nutrition. 1993. N 9. P. 452–459.</mixed-citation><mixed-citation xml:lang="en">Despres J.-P. Abdominal obesity as an important component of insulin resistance syndrome // Nutrition. 1993. N 9. P. 452–459.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Guilherme A., Virbasius J. V., Puri V. et al. Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes // Nat. Rev. Mol. Cell. Biol. 2008. Vol. 9, N 5. P. 367– 377.</mixed-citation><mixed-citation xml:lang="en">Guilherme A., Virbasius J. V., Puri V. et al. Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes // Nat. Rev. Mol. Cell. Biol. 2008. Vol. 9, N 5. P. 367– 377.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Zeyda M., Wernly B., Demyanets S. et al. Severe obesity increases adipose tissue expression of interleukin-33 and its receptor ST2, both predominantly detectable in endothelial cells of human adipose tissue // Int. J. Obes. (Lond). 2012. N 12. P. 45–53.</mixed-citation><mixed-citation xml:lang="en">Zeyda M., Wernly B., Demyanets S. et al. Severe obesity increases adipose tissue expression of interleukin-33 and its receptor ST2, both predominantly detectable in endothelial cells of human adipose tissue // Int. J. Obes. (Lond). 2012. N 12. P. 45–53.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Trauhurn P., Wood I.S. Signaling role adipose tissue: adipokines and inflammation in obesity // Biochem. Soc. Trans. 2005. N 23. Р. 1078–1081.</mixed-citation><mixed-citation xml:lang="en">Trauhurn P., Wood I.S. Signaling role adipose tissue: adipokines and inflammation in obesity // Biochem. Soc. Trans. 2005. N 23. Р. 1078–1081.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Itoch M., Suganami T., Hachiya R., Ogawa Y. Adipose Tissue Remodeling as Homeostatic Inflammation // Int. J. Inflam. 2011. Vol. 2011. P. 1–8.</mixed-citation><mixed-citation xml:lang="en">Itoch M., Suganami T., Hachiya R., Ogawa Y. Adipose Tissue Remodeling as Homeostatic Inflammation // Int. J. Inflam. 2011. Vol. 2011. P. 1–8.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Vachharajani V., Granger D. N. Adipose tissue: a motor for the inflammation associated with obesity // IUBMB Life. 2009. V. 61, N 4. P. 424–430.</mixed-citation><mixed-citation xml:lang="en">Vachharajani V., Granger D. N. Adipose tissue: a motor for the inflammation associated with obesity // IUBMB Life. 2009. V. 61, N 4. P. 424–430.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Dray C., Debard C., Jager J. et al. Apelin and APJ regulation in adipose tissue and skeletal muscle of type 2 diabetic mice and human // Am. J. Pysiol. Endocrinal. Metab. 2010. Vol. 298. P. E1161–E1169.</mixed-citation><mixed-citation xml:lang="en">Dray C., Debard C., Jager J. et al. Apelin and APJ regulation in adipose tissue and skeletal muscle of type 2 diabetic mice and human // Am. J. Pysiol. Endocrinal. Metab. 2010. Vol. 298. P. E1161–E1169.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Esteve E., Ricart W., Fernandez-Real J. M. Adipocytokines and Insulin Resistance. The possible role of lipocalin-2, retinol binding protein-4, and adiponectin // Diabetes Care. 2009. Vol. 32. P. 362–367.</mixed-citation><mixed-citation xml:lang="en">Esteve E., Ricart W., Fernandez-Real J. M. Adipocytokines and Insulin Resistance. The possible role of lipocalin-2, retinol binding protein-4, and adiponectin // Diabetes Care. 2009. Vol. 32. P. 362–367.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Falcao-Pires I., Castro-Chaves P., Miranda-Silva D. et al. Physiological, pathological and potential therapeutic roles of adipokines // Drug Discovery Today. 2012. Vol. 17. P. 880–889.</mixed-citation><mixed-citation xml:lang="en">Falcao-Pires I., Castro-Chaves P., Miranda-Silva D. et al. Physiological, pathological and potential therapeutic roles of adipokines // Drug Discovery Today. 2012. Vol. 17. P. 880–889.</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Galic S., Oakhill J. S., Steinberg G. R. Adipose tissue as an endocrine organ // Mol. Cell. Endocrinol. 2010. Vol. 316. P. 129–139.</mixed-citation><mixed-citation xml:lang="en">Galic S., Oakhill J. S., Steinberg G. R. Adipose tissue as an endocrine organ // Mol. Cell. Endocrinol. 2010. Vol. 316. P. 129–139.</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Gonzalez A., Claria J. Resolution of Adipose Tissue Inflammation // Sci. World J. 2010. Vol. 10. P. 832–856.</mixed-citation><mixed-citation xml:lang="en">Gonzalez A., Claria J. Resolution of Adipose Tissue Inflammation // Sci. World J. 2010. Vol. 10. P. 832–856.</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Kim J. Y., van de Wall E., Laplante M. et al. Obesityassociated improvements in metabolic profile through expansion of adipose tissue // J. Clin. Invest. 2007. Vol. 117, N 9. P. 2621–2637.</mixed-citation><mixed-citation xml:lang="en">Kim J. Y., van de Wall E., Laplante M. et al. Obesityassociated improvements in metabolic profile through expansion of adipose tissue // J. Clin. Invest. 2007. Vol. 117, N 9. P. 2621–2637.</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Tilg H., Moschen A. R. Inflammatory mechanisms in the regulation of insulin resistance // Mol. Med. 2008. V. 14, N 3-4. P. 222–231.</mixed-citation><mixed-citation xml:lang="en">Tilg H., Moschen A. R. Inflammatory mechanisms in the regulation of insulin resistance // Mol. Med. 2008. V. 14, N 3-4. P. 222–231.</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Holland W. L., Bikman B. T., Wang L. P. et al. Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice // J. Clin. Invest. 2011. Vol. 121. P. 1858–1870.</mixed-citation><mixed-citation xml:lang="en">Holland W. L., Bikman B. T., Wang L. P. et al. Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice // J. Clin. Invest. 2011. Vol. 121. P. 1858–1870.</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Nguyen M. T., Favelyukis S., Nguyen A.-K. et al. A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways // J. Biol. Chem. 2007. Vol. 282. P. 35279–35292.</mixed-citation><mixed-citation xml:lang="en">Nguyen M. T., Favelyukis S., Nguyen A.-K. et al. A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways // J. Biol. Chem. 2007. Vol. 282. P. 35279–35292.</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Cancello R., Henegar C., Viguerie N. et al. Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss // Diabetes. 2005. N 54. Р. 2277–2286.</mixed-citation><mixed-citation xml:lang="en">Cancello R., Henegar C., Viguerie N. et al. Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss // Diabetes. 2005. N 54. Р. 2277–2286.</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Kamei N. Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance // J. Biol. Chem. 2006. Vol. 281. P. 26602– 26614.</mixed-citation><mixed-citation xml:lang="en">Kamei N. Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance // J. Biol. Chem. 2006. Vol. 281. P. 26602– 26614.</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Kanda H. MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity // J. Clin. Invest. 2006. Vol. 116. P. 1494–1505.</mixed-citation><mixed-citation xml:lang="en">Kanda H. MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity // J. Clin. Invest. 2006. Vol. 116. P. 1494–1505.</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Guerre-Millo M. Adipose tissue and adipokines: for better or worse // Diabetes Metab. 2004. Vol. 30. P. 13–19.</mixed-citation><mixed-citation xml:lang="en">Guerre-Millo M. Adipose tissue and adipokines: for better or worse // Diabetes Metab. 2004. Vol. 30. P. 13–19.</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Kern P. A., Saghizadeh M., Ong J. M. et al. The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase // J. Clin. Invest. 1995. Vol. 95. P. 2111–2119.</mixed-citation><mixed-citation xml:lang="en">Kern P. A., Saghizadeh M., Ong J. M. et al. The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase // J. Clin. Invest. 1995. Vol. 95. P. 2111–2119.</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Плохая А. А. Современные аспекты лечения метаболического синдрома А. А. Плохая // Ожирение и метаболизм. – 2011. – № 3. – С. 31–37.</mixed-citation><mixed-citation xml:lang="en">Плохая А. А. Современные аспекты лечения метаболического синдрома А. А. Плохая // Ожирение и метаболизм. – 2011. – № 3. – С. 31–37.</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Lemieux S., Despres J.-P., Moorjani S. et al. Are gender differences in cardiovascular disease risk factors explained by the level of visceral adipose tissue? // Diabetologia. 1994. Vol. 37. P. 757–764.</mixed-citation><mixed-citation xml:lang="en">Lemieux S., Despres J.-P., Moorjani S. et al. Are gender differences in cardiovascular disease risk factors explained by the level of visceral adipose tissue? // Diabetologia. 1994. Vol. 37. P. 757–764.</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">Lonnqvist F., Thorne A., Large V., Arner P. Sex differences in visceral fat lipolysis and metabolic complications of obesity // Arterioscler. Thromb. Vasc. Biol. 1997. Vol. 17. P. 1472–1480.</mixed-citation><mixed-citation xml:lang="en">Lonnqvist F., Thorne A., Large V., Arner P. Sex differences in visceral fat lipolysis and metabolic complications of obesity // Arterioscler. Thromb. Vasc. Biol. 1997. Vol. 17. P. 1472–1480.</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Ben-Noun L., Sohar E., Laor A. Neck circumference as a simple screening measure for identifying overweight and obese patients // Obes Res. 2001. N 9 (8). P. 470.</mixed-citation><mixed-citation xml:lang="en">Ben-Noun L., Sohar E., Laor A. Neck circumference as a simple screening measure for identifying overweight and obese patients // Obes Res. 2001. N 9 (8). P. 470.</mixed-citation></citation-alternatives></ref><ref id="cit60"><label>60</label><citation-alternatives><mixed-citation xml:lang="ru">Zhou Jing-ya, Hui Ge, Zhu Ming-fan et al. Neck Circumference as an Independent Predictive Contributor to Cardio-Metabolic Syndrome // Cardiovasc. Diabetol. 2013. Vol. 112 (76).</mixed-citation><mixed-citation xml:lang="en">Zhou Jing-ya, Hui Ge, Zhu Ming-fan et al. Neck Circumference as an Independent Predictive Contributor to Cardio-Metabolic Syndrome // Cardiovasc. Diabetol. 2013. Vol. 112 (76).</mixed-citation></citation-alternatives></ref><ref id="cit61"><label>61</label><citation-alternatives><mixed-citation xml:lang="ru">Yang G. R., Yuan S. Y., Fu H. J. et al. Beijing Community Diabetes Study Group // Diabetes Care. 2010. Vol. Nov 33(11). P. 2465–2467.</mixed-citation><mixed-citation xml:lang="en">Yang G. R., Yuan S. Y., Fu H. J. et al. Beijing Community Diabetes Study Group // Diabetes Care. 2010. Vol. Nov 33(11). P. 2465–2467.</mixed-citation></citation-alternatives></ref><ref id="cit62"><label>62</label><citation-alternatives><mixed-citation xml:lang="ru">Castan-laurell I., Dray C., Knaufl C. et al. Apelin, a promising target for type 2 diabetes treatment? // Trends in Endocrinology&amp;Metabolism. 2012. Vol. 23, N 5. Р. 234–241.</mixed-citation><mixed-citation xml:lang="en">Castan-laurell I., Dray C., Knaufl C. et al. Apelin, a promising target for type 2 diabetes treatment? // Trends in Endocrinology&amp;Metabolism. 2012. Vol. 23, N 5. Р. 234–241.</mixed-citation></citation-alternatives></ref><ref id="cit63"><label>63</label><citation-alternatives><mixed-citation xml:lang="ru">Dray C., Foussal C., Attanй C. et al. Apelin: from cardiac function to energetic metabolism // Sang Thrombose Vaisseaux. 2009. Vol. 21, N 7. P. 233–240.</mixed-citation><mixed-citation xml:lang="en">Dray C., Foussal C., Attanй C. et al. Apelin: from cardiac function to energetic metabolism // Sang Thrombose Vaisseaux. 2009. Vol. 21, N 7. P. 233–240.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
