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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ateroskleroz</journal-id><journal-title-group><journal-title xml:lang="ru">Атеросклероз</journal-title><trans-title-group xml:lang="en"><trans-title>Ateroscleroz</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-256X</issn><issn pub-type="epub">2949-3633</issn><publisher><publisher-name>НИИТПМ-филиал ИЦиГ СО РАН</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ateroskleroz-35</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>РИСК РАЗВИТИЯ АССОЦИИРОВАННЫХ С АТЕРОСКЛЕРОЗОМ ЗАБОЛЕВАНИЙ (ИНФАРКТА МИОКАРДА, ИНСУЛЬТА) И ЖИЗНЕННОЕ ИСТОЩЕНИЕ У НАСЕЛЕНИЯ В РОССИИ/СИБИРИ (ПРОГРАММА ВОЗ «MONICA-ПСИХОСОЦИАЛЬНАЯ»)</article-title><trans-title-group xml:lang="en"><trans-title>THE RISK OF DEVELOPING DISEASES ASSOCIATED WITH ATHEROSCLEROSIS (MYOCARDIAL INFARCTION, STROKE) AND THE DEPLETION OF THE POPULATION LIVING IN RUSSIA / SIBERIA (WHO PROGRAM «MONICA-PSYCHOSOCIAL»)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гафаров</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gafarov</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">valery.gafarov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Громова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gromova</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гагулин</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gagulin</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Панов</surname><given-names>Д. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Panov</surname><given-names>D. O.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гафарова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gafarova</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ НИИ терапии и профилактической медицины</institution></aff><aff xml:lang="en"><institution>Institute of Internal and Preventive Medicine</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>27</day><month>09</month><year>2019</year></pub-date><volume>13</volume><issue>1</issue><fpage>19</fpage><lpage>28</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гафаров В.В., Громова Е.А., Гагулин И.В., Панов Д.О., Гафарова А.В., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Гафаров В.В., Громова Е.А., Гагулин И.В., Панов Д.О., Гафарова А.В.</copyright-holder><copyright-holder xml:lang="en">Gafarov V.V., Gromova E.A., Gagulin I.V., Panov D.O., Gafarova A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ateroskleroz.elpub.ru/jour/article/view/35">https://ateroskleroz.elpub.ru/jour/article/view/35</self-uri><abstract><p>Цель исследования: определить риск развития ассоциированных с атеросклерозом заболеваний (инфаркта миокарда и инсульта) у мужчин и женщин с жизненным истощением (ЖИ) в открытой популяции 25-64 лет в России/Сибири. Материал и методы: в рамках III скрининга программы ВОЗ «MONICA-psychosocial» обследована случайная репрезентативная выборка населения 25-64 лет г. Новосибирска в 1994 г. (657 мужчин, 870 женщин). Программа скринирующего обследования включала: регистрацию социально-демографических данных, выявление ЖИ. За 16-летний период инфаркт миокарда (ИМ) и инсульт выявлены в 15 и 35 случаях у женщин и в 30 и 22 случаях у мужчин соответственно. Результаты. Распространенность ЖИ составила у мужчин 66,8 % (высокий ЖИ - 14,6 %), у женщин - 75,7 % (высокий ЖИ - 44,4 %). Относительный риск (ОР) ИМ был выше среди мужчин с ЖИ (ОР=2), чем среди женщин. Среди разведенных лиц риск ИМ был выше у женщин (ОР=5,4), чем у мужчин (ОР=4,7). ОР ИМ был выше у мужчин с ЖИ (с начальным образованием ОР=2,2; у никогда не состоявших в браке ОР=3,7, овдовевших мужчин ОР=7, в 45-54 года ОР=3,8 и 55-64 года ОР=5,9), чем у женщин. ОР инсульта у лиц с ЖИ гендерных различий не имел (у женщин ОР=3,34, у мужчин ОР=3,1). ОР инсульта был выше у мужчин с ЖИ с незаконченным средним - начальным образованием (ОР= 4,8), среди разведенных (ОР= 3,8) и овдовевших (ОР=3,6), чем у женщин. Заключение. Установлена большая распространенность ЖИ среди населения 25-64 лет, причем у женщин выше, чем у мужчин. ЖИ в большей мере является предиктором развития ассоциированных с атеросклерозом заболеваний: инфаркта миокарда больше у мужчин, чем у женщин, и инсульта у лиц обоего пола.</p></abstract><trans-abstract xml:lang="en"><p>Objective: To determine the risk of developing diseases associated with atherosclerosis (myocardial infarction and stroke) in men and women with vital exhaustion in general in population 25-64 years in Russia / Siberia. Material and methods: In the III screening WHO program «MONICA-psychosocial» surveyed a random representative sample of the population aged 25-64 in Novosibirsk in 1994 (men = 657, women = 870). The program screened survey included: registration of socio-demographic data, identification VE. For a 16 year period it revealed a myocardial infarction (MI) and stroke in women cases (15 and 35) and male (30 and 22). Results. VE level were: men 66.8 % (-14.6 % high), 75.7 % in women (44.4 % higher). The risk of MI among men with VE was HR=2. We did not get the effect of VE on the risk MI among women. RR of MI in persons with VE were higher among divorced women HR = 5.4, than men HR = 4.7. Risk MI was higher in men with VE: primary education HR = 2.2; have never married HR = 3.7, widowed male HR = 7, in 45-54 years HR = 3.8 and HR = 55-64 5.9. In women, these associations have been identified. Risk of stroke in patients with VE were higher in women HR = 3.34, than men HR=3.1. Risk stroke was higher only in men with VE: with incomplete secondary - primary education HR = 4.8; men, divorced HR = 3.8, widowed men at HR = 3.6. Risk of stroke among people older than 55 years was higher in women HR = 2.9, than men HR = 2.4. Conclusion: Prevalence of VE was higher in women than in men. Vital exhaustion is a predictor of MI in men and stroke in both genders. VE has a large prevalence among the population aged 25-64 years, and higher in women than in men. VE is a predictor of atherosclerosis-associated diseases: myocardial infarction greater in men than in women and stroke in both sexes.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>атеросклероз</kwd><kwd>инфаркт миокарда</kwd><kwd>инсульт</kwd><kwd>жизненное истощение</kwd><kwd>риск развития</kwd><kwd>население</kwd></kwd-group><kwd-group xml:lang="en"><kwd>gender differences</kwd><kwd>vital exhaustion</kwd><kwd>the risk of myocardial infarction</kwd><kwd>stroke</kwd><kwd>population</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Appels A., Hoppener P., Mulder P. A questionnaire to assess premonitory symptoms of myocardial infarction // Int. J. Cardiol. 1987. Vol. 17. P. 15-24.</mixed-citation><mixed-citation xml:lang="en">Appels A., Hoppener P., Mulder P. A questionnaire to assess premonitory symptoms of myocardial infarction // Int. J. Cardiol. 1987. Vol. 17. 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