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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ateroskleroz</journal-id><journal-title-group><journal-title xml:lang="ru">Атеросклероз</journal-title><trans-title-group xml:lang="en"><trans-title>Ateroscleroz</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-256X</issn><issn pub-type="epub">2949-3633</issn><publisher><publisher-name>НИИТПМ-филиал ИЦиГ СО РАН</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ateroskleroz-211</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ИНФОРМАЦИОННЫЕ И МЕТОДИЧЕСКИЕ МАТЕРИАЛЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>INFORMATION AND METHODICAL MATERIAL</subject></subj-group></article-categories><title-group><article-title>КЛИНИЧЕСКИЕ РЕКОМЕНДАЦИИ ПО СЕМЕЙНОЙ ГИПЕРХОЛЕСТЕРИНЕМИИ</article-title><trans-title-group xml:lang="en"><trans-title>CLINICAL GUIDELINES FOR FAMILIAL HYPERCHOLESTEROLEMIA</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ежов</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ezhov</surname><given-names>M. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бажан</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Bazhan</surname><given-names>S. S.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ершова</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Ershova</surname><given-names>A. I.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мешков</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Meshkov</surname><given-names>A. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соколов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sokolov</surname><given-names>A. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кухарчук</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kukharchuk</surname><given-names>V. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гуревич</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Gurevich</surname><given-names>V. S.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Воевода</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Voevoda</surname><given-names>M. I.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сергиенко</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sergienko</surname><given-names>I. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шахтшнейдер</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shakhtshneider</surname><given-names>E. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Покровский</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Pokrovsky</surname><given-names>S. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коновалов</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Konovalov</surname><given-names>G. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-6"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Леонтьева</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Leontyeva</surname><given-names>I. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-7"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Константинов</surname><given-names>В. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Konstantinov</surname><given-names>V. O.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-8"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Щербакова</surname><given-names>М. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Shcherbakova</surname><given-names>M. Yu.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-9"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захарова</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakharova</surname><given-names>I. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-10"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Балахонова</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Balakhonova</surname><given-names>T. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Филиппов</surname><given-names>А. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Filippov</surname><given-names>A. E.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-11"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ахмеджанов</surname><given-names>Н. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Akhmedzhanov</surname><given-names>N. M.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Александрова</surname><given-names>О. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Aleksandrova</surname><given-names>O. Yu.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-12"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Липовецкий</surname><given-names>Б. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Lipovetsky</surname><given-names>B. M.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-13"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр кардиологии» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Institution «National Medical Research Center of Cardiology»  of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>НИИ терапии и профилактической медицины –  филиал ФГБНУ ФИЦ Институт цитологии и генетики СО РАН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Internal and Preventive Medicine – Branch of Fedaral Research Institute of Cytology and Genetics  of the Siberian Branch of the Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр профилактической медицины»  Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Institution “National Medical Research Center for Preventive Medicine”  of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Военно-медицинская академия им. С. М. Кирова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Military Medical Academy n.a. S.M. Kirov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ФГБОУ ВПО «Санкт-Петербургский государственный университет»; ФГБОУ ВО «Северо-Западный государственный медицинский университет им. И.И. Мечникова»  Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Educational Institution of Higher Professional Education “St. Petersburg State University”; North-Western State Medical University n.a. I.I.Mechnikov, Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru"><institution>Центр диагностики и инновационных медицинских технологий «КДЦ “Медси” на Белорусской»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Center for Diagnostics and Innovative Medical Technologies of the CDC Medsi in Belorusskaya</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-7"><aff xml:lang="ru"><institution>ФГБОУ ВО «Российский национальный исследовательский медицинский университет  имени Н.И. Пирогова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>SBEI of HE «NI Pirogov Russian National Research Medical University»  of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-8"><aff xml:lang="ru"><institution>ФГБОУ ВО «Северо-Западный государственный медицинский университет им. И.И. Мечникова»  Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>North-Western State Medical University n.a. I.I.Mechnikov, Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-9"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский университет дружбы народов»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>FSAEI of HE «Peoples’ Friendship University of Russia»</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-10"><aff xml:lang="ru"><institution>ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования»  Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>FGBOU DPO «Russian Medical Academy of Continuing Professional Education»  Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-11"><aff xml:lang="ru"><institution>ФГБОУ ВПО «Санкт-Петербургский государственный университет»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Educational Institution of Higher Professional Education “St. Petersburg State University”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-12"><aff xml:lang="ru"><institution>Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Regional Research Clinical Institute n.a. M.F. Vladimirsky</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-13"><aff xml:lang="ru"><institution>Институт мозга человека им. Н.П. Бехтеревой РАН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Human Brain n.a. N.P. Bekhtereva of the Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>22</day><month>12</month><year>2019</year></pub-date><volume>15</volume><issue>1</issue><fpage>58</fpage><lpage>98</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ежов М.В., Бажан С.С., Ершова А.И., Мешков А.Н., Соколов А.А., Кухарчук В.В., Гуревич В.С., Воевода М.И., Сергиенко И.В., Шахтшнейдер Е.В., Покровский С.Н., Коновалов Г.А., Леонтьева И.В., Константинов В.О., Щербакова М.Ю., Захарова И.Н., Балахонова Т.В., Филиппов А.Е., Ахмеджанов Н.М., Александрова О.Ю., Липовецкий Б.М., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Ежов М.В., Бажан С.С., Ершова А.И., Мешков А.Н., Соколов А.А., Кухарчук В.В., Гуревич В.С., Воевода М.И., Сергиенко И.В., Шахтшнейдер Е.В., Покровский С.Н., Коновалов Г.А., Леонтьева И.В., Константинов В.О., Щербакова М.Ю., Захарова И.Н., Балахонова Т.В., Филиппов А.Е., Ахмеджанов Н.М., Александрова О.Ю., Липовецкий Б.М.</copyright-holder><copyright-holder xml:lang="en">Ezhov M.V., Bazhan S.S., Ershova A.I., Meshkov A.N., Sokolov A.A., Kukharchuk V.V., Gurevich V.S., Voevoda M.I., Sergienko I.V., Shakhtshneider E.V., Pokrovsky S.N., Konovalov G.A., Leontyeva I.V., Konstantinov V.O., Shcherbakova M.Y., Zakharova I.N., Balakhonova T.V., Filippov A.E., Akhmedzhanov N.M., Aleksandrova O.Y., Lipovetsky B.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ateroskleroz.elpub.ru/jour/article/view/211">https://ateroskleroz.elpub.ru/jour/article/view/211</self-uri><abstract><p>Данные клинические рекомендации представляют все современные аспекты этиологии, диагностики и лечения семейной гиперхолестеринемии как у взрослых, так и детей. Рекомендации подготовлены для размещения в соответствующем рубрикаторе клинических рекомендаций Минздрава России в сети Интернет по адресу http://cr.rosminzdrav.ru/.</p></abstract><trans-abstract xml:lang="en"><p>These guidelines represent all current aspects of etiology, diagnosis, and treatment of the clinical and statistical group of familial hypercholesterolemia in both adults and children in accordance with the requirements of the Ministry of Health of Russia.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>семейная гиперхолестеринемия</kwd><kwd>атеросклероз</kwd><kwd>ишемическая болезнь сердца</kwd><kwd>холестерин липопротеидов низкой плотности</kwd><kwd>ксантомы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>familial hypercholesterolemia</kwd><kwd>atherosclerosis</kwd><kwd>coronary heart disease</kwd><kwd>low density lipoprotein cholesterol</kwd><kwd>xanthomas</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ежов М.В., Сергиенко И.В., Рожкова Т.А., Кухарчук В.В., Коновалов Г.А., Мешков А.Н., Ершова А.И., Гуревич В.С., Константинов В.О., Соколов А.А., Щербакова М.Ю., Леонтьева И.В., Бажан С.С., Воевода М.И., Шапошник И.И. 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