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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ateroskleroz</journal-id><journal-title-group><journal-title xml:lang="ru">Атеросклероз</journal-title><trans-title-group xml:lang="en"><trans-title>Ateroscleroz</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-256X</issn><issn pub-type="epub">2949-3633</issn><publisher><publisher-name>НИИТПМ-филиал ИЦиГ СО РАН</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52727/2078-256X-2025-21-1-23-33</article-id><article-id custom-type="elpub" pub-id-type="custom">ateroskleroz-1099</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Анализ половозрастных особенностей распространенности психосоциальных факторов риска сердечно-сосудистых заболеваний в условиях мегаполиса и крупного города Западной Сибири</article-title><trans-title-group xml:lang="en"><trans-title>Analysis of age and gender characteristics of the prevalence of psychosocial risk factors for cardiovascular diseases in a metropolis and a large city in Western Siberia</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9961-5616</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Акимова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Akimova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Екатерина Викторовна Акимова, д-р мед. наук, зав. лабораторией эпидемиологии и профилактики сердечно-сосудистых заболеваний</p><p>625026, г. Тюмень, ул. Мельникайте, 111</p></bio><bio xml:lang="en"><p>Ekaterina V. Akimova, doctor of medical sciences, head laboratory of epidemiology and prevention of cardiovasculardiseases</p><p>111, Melnikayte st., Tyumen, 625026</p></bio><email xlink:type="simple">akimovaev@infarkta.net</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5701-7856</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гафаров</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gafarov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Валерий Васильевич Гафаров, д-р мед. наук, проф., главный научный сотрудник, зав. лабораторией психологических и социологических проблем терапевтических заболеваний</p><p>630089, г. Новосибирск, ул. Бориса Богаткова, 175/1</p></bio><bio xml:lang="en"><p>Valery V. Gafarov, doctor of medical sciences, professor, head laboratory of psychological and sociological problems of therapeutic diseases</p><p>175/1, Boris Bogatkov st., Novosibirsk, 630089</p></bio><email xlink:type="simple">valery.gafarov@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5326-119X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каюмова</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kayumova</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Марина Михайловна Каюмова, канд. мед. наук, старший научный сотрудник лаборатории эпидемиологии и профилактики сердечно-сосудистых заболеваний</p><p>625026, г. Тюмень, ул. Мельникайте, 111</p></bio><bio xml:lang="en"><p>Marina M. Kayumova, candidate of medical sciences, senior researcher laboratory of epidemiology and prevention of cardiovascular diseases</p><p>111, Melnikayte st., Tyumen, 625026</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8313-3893</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Громова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gromova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Елена Алексеевна Громова, д-р мед. наук, ведущий научный сотрудник лаборатории психологических и социологических проблем терапевтических заболеваний</p><p>630089, г. Новосибирск, ул. Бориса Богаткова, 175/1</p></bio><bio xml:lang="en"><p>Elena A. Gromova, doctor of medical sciences, leading researcher laboratory of psychological and sociological problems of therapeutic diseases</p><p>175/1, Boris Bogatkov st., Novosibirsk, 630089</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8662-8760</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гакова</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Gakova</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Екатерина Ивановна Гакова, канд. мед. наук, старший научный сотрудник лаборатории эпидемиологии и профилактики сердечно-сосудистых заболеваний</p><p>625026, г. Тюмень, ул. Мельникайте, 111</p></bio><bio xml:lang="en"><p>Ekaterina I. Gakova, candidate of medical sciences, senior researcher laboratory of epidemiology and prevention of cardiovascular diseases</p><p>111, Melnikayte st., Tyumen, 625026</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5380-9434</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гафарова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gafarova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Альмира Валерьевна Гафарова, старший научный сотрудник лаборатории психологических и социологических проблем терапевтических заболеваний</p><p>630089, г. Новосибирск, ул. Бориса Богаткова, 175/1</p></bio><bio xml:lang="en"><p>Almira V. Gafarova, senior researcher at the laboratory of psychological and sociological problems of therapeutic diseases</p><p>175/1, Boris Bogatkov st., Novosibirsk, 630089</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2686-3715</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бессонова</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Bessonova</surname><given-names>M. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Марина Игоревна Бессонова, канд. мед. наук, научный сотрудник лаборатории эпидемиологии и профилактики сердечно-сосудистых заболеваний</p><p>625026, г. Тюмень, ул. Мельникайте, 111</p></bio><bio xml:lang="en"><p>Marina I. Bessonova, candidate of medical sciences, researcher laboratory of epidemiology and prevention of cardiovascular diseases</p><p>111, Melnikayte st., Tyumen, 625026</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5255-5647</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гагулин</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gagulin</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Игорь Вячеславович Гагулин, старший научный сотрудник лаборатории психологических и социологических проблем терапевтических заболеваний</p><p>630089, г. Новосибирск, ул. Бориса Богаткова, 175/1</p></bio><bio xml:lang="en"><p>Igor V. Gagulin, senior researcher at the laboratory of psychological and sociological problems of therapeutic diseases</p><p>175/1, Boris Bogatkov st., Novosibirsk, 630089</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6222-0445</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лебедев</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lebedev</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Егор Викторович Лебедев, младший научный сотрудник лаборатории эпидемиологии и профилактики сердечно-сосудистых заболеваний</p><p>625026, г. Тюмень, ул. Мельникайте, 111</p></bio><bio xml:lang="en"><p>Egor V. Lebedev, junior researcher laboratory of epidemiology and prevention of cardiovascular diseases</p><p>111, Melnikayte st., Tyumen, 625026</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4101-6079</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Новоселов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Novoselov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Антон Владиславович Новоселов, младший научный сотрудник лаборатории эпидемиологии и профилактики сердечно-сосудистых заболеваний</p><p>625026, г. Тюмень, ул. Мельникайте, 111</p></bio><bio xml:lang="en"><p>Anton V. Novoselov, junior researcher Laboratory of Epidemiology and Prevention of Cardiovascular Diseases</p><p>111, Melnikayte st., Tyumen, 625026</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5152-8460</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Акимов</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Akimov</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Александр Михайлович Акимов, канд. социoл. наук, старший научный сотрудник лаборатории эпидемиологии и профилактики сердечно-сосудистых заболеваний</p><p>625026, г. Тюмень, ул. Мельникайте, 111</p></bio><bio xml:lang="en"><p>Alexandr M. Akimov, candidate of sociological sciences, senior researcher laboratory of epidemiology and prevention of cardiovascular diseases</p><p>111, Melnikayte st., Tyumen, 625026</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Тюменский кардиологический научный центр Томского национального исследовательского медицинского центра Российской академии наук<country>Россия</country></aff><aff xml:lang="en">Tyumen Cardiology Research Center of Tomsk National Research Medical Center of Russian Academy of Sciences<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Научно-исследовательский институт терапии и профилактической медицины – филиал Федерального государственного бюджетного научного учреждения «Федеральный исследовательский центр Институт цитологии и генетики Сибирского отделения Российской академии наук»<country>Россия</country></aff><aff xml:lang="en">Research Institute of Internal and Preventive Medicine – Branch of the Institute of Cytology and Genetics, Siberian branch of Russian Academy of Sciences<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>29</day><month>03</month><year>2025</year></pub-date><volume>21</volume><issue>1</issue><fpage>23</fpage><lpage>33</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Акимова Е.В., Гафаров В.В., Каюмова М.М., Громова Е.А., Гакова Е.И., Гафарова А.В., Бессонова М.И., Гагулин И.В., Лебедев Е.В., Новоселов А.В., Акимов А.М., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Акимова Е.В., Гафаров В.В., Каюмова М.М., Громова Е.А., Гакова Е.И., Гафарова А.В., Бессонова М.И., Гагулин И.В., Лебедев Е.В., Новоселов А.В., Акимов А.М.</copyright-holder><copyright-holder xml:lang="en">Akimova E.V., Gafarov V.V., Kayumova M.M., Gromova E.A., Gakova E.I., Gafarova A.V., Bessonova M.I., Gagulin I.V., Lebedev E.V., Novoselov A.V., Akimov A.M.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ateroskleroz.elpub.ru/jour/article/view/1099">https://ateroskleroz.elpub.ru/jour/article/view/1099</self-uri><abstract><p>Цель исследования – изучить сравнительные характеристики распространенности психосоциальных факторов (ПСФ) риска в условиях крупнейшего (мегаполиса) и крупного города Западной Сибири среди лиц 25–64 лет. Материал и методы. Обследованы репрезентативные выборки лиц 25–64 лет мегаполиса Западной Сибири (г. Новосибирск) и крупного сибирско- го города (г. Тюмень) в 2010–2013 и 2015–2017 гг. Оценка уровня личностной тревожности (ЛТ), жизненного истощения (ЖИ), депрессии (Д) проводилась по стандартным методикам протокола программы ВОЗ «MONICA-психосоциальная». Результаты. Анализ показал, что в мегаполисе Западной Сибири распространенность высокого уровня ЛТ и Д превалировала над распространенностью ПСФ в крупном сибирском городе – у мужчин младших возрастных групп 25–34 лет (Д) и 35–44 лет (ЛТ, Д); у женщин крайних возрастных групп 25–34 и 55–64 лет (Д). В крупном сибирском городе распространенность высокого уровня некоторых ПСФ преобладала над их распространенностью в мегаполисе Западной Сибири – у мужчин старшей возрастной группы 55–64 лет (Д), у женщин 25–34 лет (ЖИ) и 45–54 лет (ЛТ). Заключение. Таким образом, результаты исследования ПСФ риска сердечно-сосудистых заболеваний у мужчин и женщин экономически эффективного возраста на открытых городских популяциях крупнейшего (мегаполиса) и крупного городов Западной Сибири продемонстрировали существенные различия по распространенности ПСФ в различных возрастных категориях и тем самым показали необходимость оценки ПСФ при планировании профилактических программ в сибирских городах.</p></abstract><trans-abstract xml:lang="en"><p>This study aimed to compare the prevalence of psychosocial risk factors for cardiovascular disease (CVD) among adults aged 25–64 in the largest metropolis (Novosibirsk) and a large city (Tyumen) in Western Siberia. Material and methods Representative samples of adults aged 25–64 from Novosibirsk (metropolis) and Tyumen (large city) were examined between 2010–2013 and 2015–2017. Psychosocial factors, including personal anxiety (PA), vital exhaustion (VE), and depression (D), were assessed using standardized methods from the WHO MONICA-psychosocial program protocol. Results. In the Siberian metropolis, higher prevalence rates of elevated PA and D were observed compared to the large city: in men in younger age groups (25–34 years for D; 35–44 years for PA and D); in women in extreme age groups (25–34 and 55–64 years for D). Conversely, the large city showed higher prevalence rates for certain psychosocial factors: in men in older age group (55–64 years for D). and in women in younger (25–34 years for VE) and middle-aged (45–54 years for PA) groups. Conclusions. Significant differences in the prevalence of psychosocial CVD risk factors were identified across age categories in urban populations of Western Siberia. These findings underscore the importance of tailoring preventive programs to address age- and location-specific risk profiles in Siberian cities.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>мегаполис</kwd><kwd>крупный город Западной Сибири</kwd><kwd>психосоциальные факторы риска</kwd><kwd>личностная тревожность</kwd><kwd>депрессия</kwd><kwd>жизненное истощение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>metropolis</kwd><kwd>large city of Western Siberia</kwd><kwd>psychosocial risk factors</kwd><kwd>personal anxiety</kwd><kwd>depression</kwd><kwd>life exhaustion</kwd></kwd-group><funding-group xml:lang="ru"><funding-statement>Исследование выполнено в рамках бюджетных тем: Тюменский кардиологический центр – филиал Томского НИМЦ, рег. № НИОКТР: 122020300112-4; НИИ терапии и профилактической медицины – филиала Института цитологии и генетики СО РАН, рег. № FWNR-2024-0002.</funding-statement></funding-group><funding-group xml:lang="en"><funding-statement>The study was carried out within the framework of budget themes: Tyumen Cardiology Center – branch of Tomsk National Research Medical Center, Reg. No. NIOKTR: 122020300112-4; Research Institute of Therapy and Preventive Medicine – branch of the Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences, Reg. No. FWNR-2024-0002.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Okereke O., Manson J.E. Psychosocial factors and cardiovascular disease risk: An opportunity in women’s health, Circ. Res., 2017; 120 (12): 1855–1856. doi: 10.1161/CIRCRESAHA.117.311113</mixed-citation><mixed-citation xml:lang="en">Okereke O., Manson J.E. Psychosocial factors and cardiovascular disease risk: An opportunity in women’s health, Circ. 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